6 Result(s)
within
Andreas Kurtz
English
Medicine/Public Health, general
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Article
Open AccessImpact of heart failure on the behavior of human neonatal stem cells in vitro
Clinical cardiac cell therapy using autologous somatic stem cells is restricted by age and disease-associated impairment of stem cell function. Juvenile cells possibly represent a more potent alternative, but ...
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Article
Open AccessSerum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors
Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome characterized by the development of benign nerve-sheath tumors, which transform to malignant peripheral nerve-sheath tumors (MPNST) in about 8 to 1...
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Article
Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids
Neurofibromatosis type 1 (NF1) is a common genetic disorder of the nervous system resulting in neurofibromas and malignant peripheral nerve sheath tumors (MPNST). In this study, we report the modulation of mur...
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Article
The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells
Loss of the tumor suppressor gene NF1 in neurofibromatosis type 1 (NF1) contributes to the development of a variety of tumors, including malignant peripheral nerve sheath tumors (MPNST) and benign neurofibromas. ...
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Article
Breast cancer growth inhibition by delivery of the MDGI-derived peptide P108
Mammary derived growth inhibitor (MDGI) is a member of the family of cytoplasmic fatty acid binding proteins (FABPs), which bind hydrophobic ligands such as fatty acids, retinoids, eicosanoids and prostaglandi...
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Article
Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis
Fibroblast growth factors (FGF)-1 and -2 are found in most embryonic and adult normal and tumor tissues, where they are immobilized in the extracellular matrix (EM). Mobilization of these FGFs is part of a tig...
