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  1. No Access

    Reference Work Entry In depth

    Retinoids and Reactive Oxygen Species in Cancer Cell Death and Therapeutics

    Retinoids are a large family of structurally related natural and synthetic molecules that exhibit a variety of effects in embryogenesis and adult life. The parent compound of retinoids is vitamin A which was f...

    Chirine El-Baba, Ali H. Eid, Abdallah Shaito… in Handbook of Oxidative Stress in Cancer: Me… (2022)

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    Article

    Terpenoids’ anti-cancer effects: focus on autophagy

    Terpenoids are the largest class of natural products, most of which are derived from plants. Amongst their numerous biological properties, their anti-tumor effects are of interest for they are extremely divers...

    Chirine El-Baba, Amro Baassiri, Georges Kiriako, Batoul Dia, Sukayna Fadlallah… in Apoptosis (2021)

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    Living Reference Work Entry In depth

    Retinoids and Reactive Oxygen Species in Cancer Cell Death and Therapeutics

    Retinoids are a large family of structurally related natural and synthetic molecules that exhibit a variety of effects in embryogenesis and adult life. The parent compound of retinoids is vitamin A which was f...

    Chirine El-Baba, Ali H. Eid, Abdallah Shaito… in Handbook of Oxidative Stress in Cancer: Me…

  4. No Access

    Article

    Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis

    Despite remarkable progress in the discovery and development of novel cancer therapeutics, cancer remains the second leading cause of death in the world. For many years, compounds derived from plants have been...

    Hala Gali-Muhtasib, Raed Hmadi, Mike Kareh, Rita Tohme, Nadine Darwiche in Apoptosis (2015)

  5. No Access

    Article

    Synergistic anticancer activities of the plant-derived sesquiterpene lactones salograviolide A and iso-seco-tanapartholide

    We have previously shown that the two sesquiterpene lactones, salograviolide A (Sal A) and iso-seco-tanapartholide (TNP), isolated from the Middle Eastern indigenous plants Centaurea ainetensis and Achillea falca...

    Mohamed Salla, Isabelle Fakhoury, Najat Saliba… in Journal of Natural Medicines (2013)

  6. Article

    Open Access

    Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells

    Sesquiterpene lactones (SL) are plant secondary metabolites that are known for their anti-fungal, anti-bacterial, anti-inflammatory, and anti-tumor properties. Considering that several SL-derived drugs are cur...

    Melody Saikali, Akram Ghantous, Racha Halawi… in BMC Complementary and Alternative Medicine (2012)

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    Article

    Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis

    Fibroblast growth factors (FGF)-1 and -2 are found in most embryonic and adult normal and tumor tissues, where they are immobilized in the extracellular matrix (EM). Mobilization of these FGFs is part of a tig...

    Andreas Kurtz, Huey-Lin Wang, Nadine Darwiche, Violaine Harris, Anton Wellstein in Oncogene (1997)