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Article
Current approaches in glioblastoma multiforme immunotherapy
Glioblastoma multiform (GBM) is the most prevalent CNS (central nervous system) tumor in adults, with an average survival length shorter than 2 years and rare metastasis to organs other than CNS. Despite exten...
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Article
Investigating the effect of LncRNA DLGAP1-AS2 suppression on chemosensitivity of gastric cancer to chemotherapy
Gastric cancer, as the fifth most frequent disease and the fourth foremost cause of cancer-related death worldwide, remains a main clinical challenge due to its poor prognosis, limited treatment choices, and a...
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Article
Let-7a-3p overexpression increases chemosensitivity to carmustine and synergistically promotes autophagy and suppresses cell survival in U87MG glioblastoma cancer cells
In terms of primary brain tumors, glioblastoma is one of the most aggressive and common brain tumors. The high resistance of glioblastoma to chemotherapy has made it vital to find alternative treatments and bi...
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Article
Open AccessExploring the dynamic interplay between exosomes and the immune tumor microenvironment: implications for breast cancer progression and therapeutic strategies
Breast cancer continues to pose a substantial worldwide health concern, demanding a thorough comprehension of the complex interaction between cancerous cells and the immune system. Recent studies have shown th...
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Article
Open AccessDownregulation of long noncoding RNA B4GALT1-AS1 is associated with breast cancer development
The misregulation of long non-coding RNAs (lncRNAs) is related to the progressive evolution of various human cancers, such as Breast cancer (BC). The role of lncRNA B4GALT1-AS1 has been investigated in some hu...
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Article
Open AccessTherapeutic effect of microRNA-21 on differentially expressed hub genes in gastric cancer based on systems biology
Gastric cancer (GC) is a leading cause of mortality for many people. Cancer’s initiating factors are poorly understood. miR-21 has a crucial function in several malignancies, particularly GC. Furthermore, it h...
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Article
Synergistic anticancer effects of curcumin and crocin on human colorectal cancer cells
Curcumin, a polyphenol compound derived from the Curcuma longa L, and crocin, a hydrophilic carotenoid from Crocus Sativus Linnaeus, are traditionally used in food preparations in many countries and could act ...
