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Article
Open AccessApplications of extraembryonic tissue-derived cells in vascular tissue regeneration
Vascular tissue engineering is a promising approach for regenerating damaged blood vessels and develo** new therapeutic approaches for heart disease treatment. To date, different sources of cells have been r...
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Article
Open AccessBI-847325, a selective dual MEK and Aurora kinases inhibitor, reduces aggressive behavior of anaplastic thyroid carcinoma on an in vitro three-dimensional culture
Anaplastic thyroid carcinoma (ATC) is the most aggressive subtype of thyroid cancer. In this study, we used a three-dimensional in vitro system to evaluate the effect of a dual MEK/Aurora kinase inhibitor, BI-...
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Article
Open AccessAlginate-based 3D cell culture technique to evaluate the half-maximal inhibitory concentration: an in vitro model of anticancer drug study for anaplastic thyroid carcinoma
Three-dimensional (3D) cell culture methods are identified for simulating the biological microenvironment and demonstrating more similarity to in vivo circumstances. Anaplastic thyroid carcinoma (ATC) is a let...
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Article
Application of nano-based systems for drug delivery and targeting: a review
Over the last decades, magnificent progress in the field of nanopharmaceuticals mostly with sizes smaller than 100 nm has led to the development of novel delivery systems and brightened the hope of finding new...
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Article
Immobilized Laminin-derived Peptide Can Enhance Expression of Stemness Markers in Mesenchymal Stem Cells
Due to number of reasons such as ease of isolation and their broad differentiation capability, adult human mesenchymal stem cells (MSCs) are widely considered as of the most promising cells for regenerative me...
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Article
Transcript-level regulation of MALAT1-mediated cell cycle and apoptosis genes using dual MEK/Aurora kinase inhibitor “BI-847325” on anaplastic thyroid carcinoma
Anaplastic thyroid carcinoma (ATC) is the most lethal malignancy in thyroid carcinomas. Long non-coding RNAs (lncRNAs) are a member of non-coding RNAs, regulating the expression of gene. Metastasis-associated ...
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Article
Open AccessA critical role for miR-184 in the fate determination of oligodendrocytes
New insights on cellular and molecular aspects of both oligodendrocyte (OL) differentiation and myelin synthesis pathways are potential avenues for develo** a cell-based therapy for demyelinating disorders c...
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Article
Influence of Chitosan Molecular Weight and Poly(ethylene oxide): Chitosan Proportion on Fabrication of Chitosan Based Electrospun Nanofibers
Fabrication of electrospun chitosan nanofibers is still a controversial issue in publications. Although regarding the lots of reports, mixtures of chitosan with a hydrophilic synthetic polymer such as polyethy...
