36 Result(s)
within
Hossein Naderi-Manesh
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Article
Open AccessLabel-free electrochemical cancer cell detection leveraging hemoglobin-encapsulated silver nanoclusters and Cu-MOF nanohybrids on a graphene-assisted dual-modal probe
Breast cancer detection at an early stage significantly increases the chances of successful treatment and survival. This study presents an electrochemical biosensor for detecting breast cancer cells, utilizing...
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Open AccessQuantifying F-actin patches in single melanoma cells using total-internal reflection fluorescence microscopy
Total-internal reflection fluorescence (TIRF) microscope is a unique technique for selective excitation of only those fluorophore molecules in a cellular environment, which are located at the sub-diffraction a...
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Open AccessDesign and simulation of the liposomal model by using a coarse-grained molecular dynamics approach towards drug delivery goals
The simulated liposome models provide events in molecular biological science and cellular biology. These models may help to understand the cell membrane mechanisms, biological cell interactions, and drug deliv...
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Open AccessMicrofluidic investigation of the effect of graphene oxide on mechanical properties of cell and actin cytoskeleton networks: experimental and theoretical approaches
Biomechanical and morphological analysis of the cells is a novel approach for monitoring the environmental features, drugs, and toxic compounds’ effects on cells. Graphene oxide (GO) has a broad range of medic...
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Morphometry and Modeling of Label-Free Human Melanocytes and Melanoma Cells
A combination of light microscopy and image processing was applied to investigate morphology of label-free primary-melanocytes and melanoma cells. A novel methodological approach based on morphology of nuclear...
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Open AccessA combined microfluidic deep learning approach for lung cancer cell high throughput screening toward automatic cancer screening applications
Lung cancer is a leading cause of cancer death in both men and women worldwide. The high mortality rate in lung cancer is in part due to late-stage diagnostics as well as spread of cancer-cells to organs and t...
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Investigation of Atrial Natriuretic Peptide as A Competitive Inhibitory Candidate Against Wnt/β-Catenin Signalling: A Molecular Dynamics Approach
Wnt/β-catenin signaling, a highly evolutionary conserved pathway, is abnormally regulated in many human cancers. This pathway is one of the proposed mechanisms of atrial natriuretic peptide (ANP) anti-cancer e...
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Antioxidant enzyme regulating and intracellular ROS scavenging capacities of two novel bioactive peptides from white grub larvae (Polyphylla adstpersa) hydrolysate in A549 cells
This study is aimed at extracting and purifying bioactive peptides from white grub larvae (Polyphylla adspersa) hydrolysate and examining their antioxidant effects on lung cancer cells (A549). Bioactive peptides ...
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Investigation of the programmed cell death by encapsulated cytoskeleton drug liposomes using a microfluidic platform
The low membrane permeability of lipophilic drugs was resolved using liposomes as a solubilizing agent and the precise size control of them is a significant parameter in drug carrier technology. Here, we have ...
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Open AccessSeed-mediated Electrochemically Developed Au Nanostructures with Boosted Sensing Properties: An Implication for Non-enzymatic Glucose Detection
A new approach has been developed to improve sensing performances of electrochemically grown Au nanostructures (AuNSs) based on the pre-seeding of the electrode. The pre-seeding modification is simply carried ...
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Application of ANN and RSM techniques for modeling electrospinning process of polycaprolactone
Due to increasing application of nanofibers in many research fields, comprehensive knowledge of the electrospinning process as the most popular method of fiber production is essential. Modeling techniques are ...
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Article
Influence of Chitosan Molecular Weight and Poly(ethylene oxide): Chitosan Proportion on Fabrication of Chitosan Based Electrospun Nanofibers
Fabrication of electrospun chitosan nanofibers is still a controversial issue in publications. Although regarding the lots of reports, mixtures of chitosan with a hydrophilic synthetic polymer such as polyethy...
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Hemoglobin-incorporated iron quantum clusters as a novel fluorometric and colorimetric probe for sensing and cellular imaging of Zn(II) and cysteine
The authors describe a novel water-soluble, stable, biocompatible, and highly fluorescent probe consisting of iron quantum clusters incorporated into human adult hemoglobin (Hb-FeQCs). The Hb-FeQCs were charac...
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Prediction of diameter in blended nanofibers of polycaprolactone-gelatin using ANN and RSM
Fabrication of nanofibers with a defined diameter is a primary purpose of the electrospinning process. The diameter of nanofiber is directly related to its individual features, such as mechanical property and ...
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Article
Open AccessEvidence of Multi-Domain Morphological Structures in Living Escherichia coli
A combination of light-microscopy and image processing was used to elaborate on the fluctuation in the width of the cylindrical part of Escherichia coli at sub-pixel-resolution, and under in vivo conditions. The ...
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Polyurethane/siloxane membranes containing graphene oxide nanoplatelets as antimicrobial wound dressings: in vitro and in vivo evaluations
Preserving wounds from bacterial and fungal infections and retaining optimum moist environment over damaged tissue are major challenges in wound care management. Application of wound dressings with antimicrobi...
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MicroRNA-145-based differentiation of human mesenchymal stem cells to smooth muscle cells
To investigate the role of microRNA-145, that regulates gene expression of genes related to differentiation, proliferation and the phenotype of smooth muscle cells (SMCs), in the differentiation of human bone ...
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In Vivo study of naturally deformed Escherichia coli bacteria
A combination of light-microscopy and image processing has been applied to study naturally deformed Escherichia coli under in vivo condition and at the order of sub-pixel high-resolution accuracy. To classify def...
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The effect of chitosan-tripolyphosphate nanoparticles on maturation and function of dendritic cells
Nanoparticles can decrease the defects of usual drug and gene delivery systems. Chitosan is a low-toxicity, biodegradable, biocompatible, and safe polymer which is used in the production of nanoparticles. Nano...
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The novel albumin–chitosan core–shell nanoparticles for gene delivery: preparation, optimization and cell uptake investigation
Natural polymers and proteins such as chitosan (CS) and albumin (Alb) have recently attracted much attention both in drug delivery and gene delivery. The underlying rationale is their unique properties such as...
