4 Result(s)

Article

WNT signalling control by KDM5C during development affects cognition

Although KDM5C is one of the most frequently mutated genes in X-linked intellectual disability¹, the exact mechanisms that lead to cognitive impairment remain unknown. Here we use human patient-derived induced pl...

Violetta Karwacki-Neisius, Ahram Jang, Engin Cukuroglu, Albert Tai, Alan Jiao… in Nature (2024)

Article

3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumors

Dynamic alterations in the unique brain extracellular matrix (ECM) are involved in malignant brain tumors. Yet studies of brain ECM roles in tumor cell behavior have been difficult due to lack of access to the...

Disha Sood, Min Tang-Schomer, Dimitra Pouli, Craig Mizzoni… in Nature Communications (2019)

Chapter and Conference Paper

Towards Reasoning About Pivoting in Startups and Large Enterprises with i*

Many start-ups fail, or are abandoned, due to flawed reasoning underpinning their products, business models, and engines of growth. Similarly, many strategic initiatives in large enterprises fail, or are deco...

Vik Pant, Eric Yu, Albert Tai in The Practice of Enterprise Modeling (2017)

Article

SCNP identifies CLL donor subgroups by profiling functional immune signaling in the context of immune modulatory receptor expression

Erwan Le Scolan, Christie Fanton, Andy Conroy… in Journal for ImmunoTherapy of Cancer (2015)