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Article
Magnetic resonance imaging of acute intracerebral hematomas: In vivo and in vitro studies
The mechanisms causing unclear differentiation of ICH in the acute phase by MRI are discussed. The increase of the hemoglobin concentration in the hematoma, caused by loss of the plasma component directly afte...
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Article
Symptomatic subependymoma with nuclear polymorphism
Two patients with symptomatic subependymomas are described. Histologically prominent cellular polymorphism was revealed. The existence of subependymoma with unusually marked polymorphism of the tumor cells sho...
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Chapter
Prediction of the Reversibility of the Brain Stem Dysfunction in Head Injury Patients: MRI and Auditory Brain Stem Response Study
16 cases of head injury patients were examined by magnetic resonance imaging (MRI) and auditory brain stem response (ABR) simultaneously in acute stage in order to investigate the possibility of the prediction...
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Article
Localization of gelatinase activities in glioma tissues by film in situ zymography
Malignant gliomas are characterized by their invasiveness and angiogenesis, which are mediated by metalloproteinases (MMPs). In this study, localization of gelatinase activities in six cases of glioblastoma, t...
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Article
Myelopathy caused by tics in an adolescent, associated with T2 signal intensity changes of the spinal cord
Course: A 15-year-old boy who had suffered motor tics since age 9 developed progressive cervical myelopathy involving both his hands and his lower extremities. T2-weighted MRI revealed mild canal...
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Article
Angiogenesis and antiangiogenic therapy for malignant gliomas
Angiogenesis is crucial to the growth of malignant gliomas. Therefore, antiangiogenic therapy represents a new, promising therapeutic modality for malignant gliomas. This study was designed to define the malig...
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Article
Endoscopic observation of pathophysiology of ventricular diverticulum
Although there have been reports dealing with ventricular diverticulum (VD) analyzed by cisternography and computed tomography (CT), those focusing on magnetic resonance imaging (MRI) or neuroendoscopic findin...
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Article
Proton magnetic resonance spectroscopy and 201Thallium-, 99m Technetium methoxyisobutylisonitrile single photon emission computed tomography findings of a patient with choroid plexus papilloma
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Article
Absolute choline concentration measured by quantitative proton MR spectroscopy correlates with cell density in meningioma
This study was aimed to investigate the relationship between quantitative proton magnetic resonance spectroscopy (1H-MRS) and pathological changes in meningioma.
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Article
Factors affecting neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture
The purpose of this study was to examine factors affecting the severity of neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture (OV...
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Article
Cystic neurohypophysial germinoma associated with moyamoya disease
Moyamoya disease associated with a germinoma has never yet been reported in the literature. This report describes a case of a cystic neurohypophysial germinoma associated with moyamoya disease. A 15-year-old g...
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Article
Detection of failure of bevacizumab treatment for malignant glioma based on urinary matrix metalloproteinase activity
Although antiangiogenic treatment for malignant glioma using bevacizumab in combination with irinotecan chemotherapy has a promising effect on survival, the high incidence of increasing infiltrative tumors can...
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Article
Epileptogenic glioma in a 4-year-old child: a case report
We report a rare case of epileptogenic glioma composed of glial progenitor cells that differentiated into an astrocytic and oligodendrocytic tumor. This 4-year-old girl presented with a 1-year history of compl...
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Chapter
Malignant Brain Tumors: Role of Radioresponsive Gene Therapy
Patients with malignant gliomas have a very poor prognosis. To explore a novel and more effective approach for the treatment of malignant gliomas, a strategy combining suicide gene therapy and radiation treatm...
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Article
Erratum to: Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing
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Article
Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing
Isocitrate dehydrogenase 1 (IDH1) mutations have recently been identified as early and frequent genetic alterations in astrocytomas, oligodendrogliomas, and oligoastrocytomas, as well as secondary glioblastoma...
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Article
Guideline for management and treatment of fetal and congenital hydrocephalus: Center Of Excellence—Fetal and Congenital Hydrocephalus Top 10 Japan Guideline 2011
Hydrocephalus does not indicate a single clinical entity, but includes a variety of clinicopathological conditions caused by excessive cerebrospinal fluid (CSF) based on the disturbed circulation. Recent progr...
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Chapter and Conference Paper
Decrease in the Apparent Diffusion Coefficient in Peritumoral Edema for the Assessment of Recurrent Glioblastoma Treated by Bevacizumab
Purposes: Anti-edema effect of bevacizumab was evaluated using the apparent diffusion coefficient (ADC) of peritumoral edema associated with regional cerebral blood flow (rCBV) of the tumor.
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Article
Benign spinal meningioma without dural attachment presenting delayed CSF dissemination and malignant transformation
Benign spinal meningiomas have good prognoses, with low rates of recurrence and no cerebrospinal fluid (CSF) dissemination. However, we experienced an extremely rare case of initially benign non-dura-based spi...
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Article
Clinical characteristics of intraspinal facet cysts following microsurgical bilateral decompression via a unilateral approach for treatment of degenerative lumbar disease
Primary intraspinal facet cysts in the lumbar spine are uncommon, but it is unclear whether cyst incidence increases following decompression surgery and if these cysts negatively impact clinical outcome. We ex...