Abstract
Moyamoya disease associated with a germinoma has never yet been reported in the literature. This report describes a case of a cystic neurohypophysial germinoma associated with moyamoya disease. A 15-year-old girl with central diabetes insipidus was admitted to the hospital. Radiological examination revealed a suprasellar tumor and moyamoya disease. Surgery and pathological study confirmed pure germinoma. After the patient was treated with radiation and chemotherapy, the tumor was controlled without any effect on the moyamoya vessels. This report describes a rare incidental combination of moyamoya disease and a suprasellar germinoma. In the management of such cases, physicians should be aware of the symptoms, course, and natural history of both diseases and the effects and side effects of each type of therapy.
References
Aihara N, Nagai H, Mase M, Kanai H, Wakabayashi S, Mabe H (1992) Atypical moyamoya disease associated with brain tumor. Surg Neurol 37:46–50
Arita K, Uozumi T, Oki S, Kuwabara S, Ohba S, Nakahara T et al (1992) Moyamoya disease associated with pituitary adenoma—report of two cases. Neurol Med Chir (Tokyo) 32:753–757
Hattori M, Tokunaga J, Toya S, Shizawa H (1973) An occlusion of the circle of Willis after the removal of cerebellar astrocytoma. No to Hattatsu 5:314–319 (Japanese with English abstract)
Kaku M, Nakayama T, Matsukado Y (1973) Surgical case of meningioma associated with basal abnormal vascular network: author translation. Shujyutsu 27:1159–1162 (Japanese)
Kitano S, Sakamoto H, Fujitani K, Kobayashi Y (2000) Moyamoya disease associated with a brain stem glioma. Childs Nerv Syst 16:251–255
Lau YL, Milligan DW (1986) Atypical presentation of craniopharyngioma associated with moyamoya disease. J R Soc Med 79:236–237
Matsutani M (2001) Combined chemotherapy and radiation therapy for CNS germ cell tumors—the Japanese experience. J Neurooncol 54:311–316
Mizukawa N, Iwatsuki K (1973) Case of cerebral basal rete mirable associated with brain tumor. Rinsho Shinkeigaku 13:650–657 (Japanese with English abstract)
Mori K, Takeuchi J, Ishikawa M, Handa H, Toyama M, Yamaki T (1978) Occlusive arteriopathy and brain tumor. J Neurosurg 49:22–35
Osuka S, Tsuboi K, Takano S, Ishikawa E, Matsushita A, Tokuuye K et al (2007) Long-term outcome of patients with intracranial germinoma. J Neurooncol 83:71–79
Suzuki K, Sonobe M, Matsutani M, Sugita K, Takahashi S (1999) Suprasellar cystic germinoma. Childs Nerv Syst 15:134–136
Tada T, Ishii K, Oshima S, Hara H, Kobayashi S (1992) Secretory meningioma associated with numerous meningothelial rosettes. Acta Neuropathol 84:342–345
Uchida K, Arakawa Y, Ohyama K, Sirakawa M, Tsuji R, Yokoyama M et al (2003) Growth hormone-secreting pituitary adenoma associated with primary moyamoya disease—case report. Neurol Med Chir (Tokyo) 43:356–359
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Shibata, Y., Matsuda, M., Suzuki, K. et al. Cystic neurohypophysial germinoma associated with moyamoya disease. Neurol Sci 31, 189–192 (2010). https://doi.org/10.1007/s10072-009-0172-1
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DOI: https://doi.org/10.1007/s10072-009-0172-1