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  1. No Access

    Article

    Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles

    Patients with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) have distinct clinical and biological features. Whereas most DS-ALL cases lack the sentinel cytogenetic lesions that guide risk assignmen...

    M G Loudin, J Wang, H-C Eastwood Leung, S Gurusiddappa, J Meyer, G Condos… in Leukemia (2011)

  2. No Access

    Article

    Improved solid phase synthesis of luteinizing hormone releasing hormone analogues using 9-fluorenylmethyloxycarbonyl amino acid active esters and catalytic transfer hydrogenation with minimal side-chain protection and their biological activities

    Using mainly 9-fluorenylmethyloxycarbonyl amino acid 2, 4, 5-trichlorophenyl esters in the presence of 1-hydroxybenzotriazole and the solid supportp-alkoxybenzyl alcohol resin, synthesis of luteinizing hormone re...

    K. M. Sivanandaiah, S. Gurusiddappa, D. Channe Gowda… in Journal of Biosciences (1989)

  3. No Access

    Article

    New analogues of leucine-methionine-enkephalin

    Nine analogues of the opioid pentapeptides leucine-/ methionine-enkephalinamide, involving replacement of amino acid at position 5 or amino acids at positions 2 and 5, have been synthesized by the solid phase ...

    K. M. Sivanandaiah, S. Gurusiddappa, D. Channe Gowda in Journal of Biosciences (1988)

  4. No Access

    Article

    Synthesis and biological activity of some new leucine-enkephalin analogues

    The opioid pentapeptide leucine-enkephalinamide and eleven of its analogues have been synthesised by the solid phase technique employing mostly 9-fluoroenylmethyloxycarbonyl amino acid active esters in the pre...

    K. M. Sivanandaiah, S. Gurusiddappa, N. S. Rangaraju in Journal of Biosciences (1985)