Skip to main content

4 Result(s)

within A. Leitch Remove this filter

and

  1. No Access

    Article

    Concerted evolution rapidly eliminates sequence variation in rDNA coding regions but not in intergenic spacers in Nicotiana tabacum allotetraploid

    Nicotiana tabacum (tobacco) is a natural allotetraploid that formed from two diploid progenitors (N. sylvestris—S-genome, N. tomentosiformis—T-genome) within past 0.2 million years. Previ...

    J. Lunerová, S. Renny-Byfield, R. Matyášek, A. Leitch… in Plant Systematics and Evolution (2017)

  2. Article

    Open Access

    Defective removal of ribonucleotides from DNA promotes systemic lupus erythematosus

    C Günther, B Kind, MAM Reijns, N Berndt, M Martinez-Bueno, C Wolf… in Pediatric Rheumatology (2015)

    Download PDF (268 KB) View Article

  3. Article

    Open Access

    Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma

    Thymidylate synthase (TS) is a key enzyme in DNA synthesis and is inhibited by metabolites of the chemotherapeutic agent 5-fluorouracil (5FU). Nuclear expression of TS in human tissue in vivo has not been char...

    N A C S Wong, L Brett, M Stewart, A Leitch, D B Longley… in British Journal of Cancer (2001)

    Download PDF (689 KB)

  4. No Access

    Article

    A trial of four anti-depressant drugs

    A trial of four anti-depressant drugs is described. The patients were assessed at the end of the four weeks without the doctor knowing which drug the patient had been receiving.

    A. Leitch, C. P. Seager in Psychopharmacologia (1963)