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Article
Plasma levels of sulfinpyrazone and of two of its metabolites after a single dose and during the steady state
The pharmacokinetics of sulfinpyrazone, and the plasma levels of its sulfide and sulfone metabolites, have been determined after a single oral dose (400 mg) and during steady-state conditions (4×200 mg daily f...
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Article
A comparative investigation of nimorazole and misonidazole as hypoxic radiosensitizers in a C3H mammary carcinoma in vivo
The hypoxic cell radiosensitizing properties of nimorazole have been investigated in a C3H mammary carcinoma transplanted to the feet of C3D2F1. The results have been compared with those obtained with misonida...
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Article
Clinical Pharmacokinetics and Potentially Important Drug Interactions of Sulphinpyrazone
Sulphinpyrazone is a derivative of Phenylbutazone. It was originally introduced as a uricosuric agent but in recent years it has been investigated for effects on platelet function.
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Chapter and Conference Paper
Klinische Pharmakologie
Seit vielen Jahren gehört Theophyllin zur Basismedikation der Behandlung der obstruktiven Komponente von Atemwegserkrankungen. Die weit verbreitete Anwendung dieses Medikamentes einerseits und die enge therape...