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Article
Acarbose for the prevention of Type 2 diabetes, hypertension and cardiovascular disease in subjects with impaired glucose tolerance: facts and interpretations concerning the critical analysis of the STOP-NIDDM Trial data
The STOP-NIDDM Trial has shown that acarbose treatment in subjects with impaired glucose tolerance is associated with a significant risk reduction in the development of diabetes, hypertension and cardiovascula...
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Article
Increased insulin-like growth factor binding protein-2 (IGFBP-2) gene expression and protein production lead to high IGFBP-2 content in malignant ovarian cyst fluid
Expression of insulin-like growth factor-I (IGF-I), its receptor and IGF-binding proteins (IGFBPs) by ovarian cancer cells and its mitogenic effect on these cells in vitro, suggest that IGF-I may have a role i...
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Article
IGF-1 AND IGFBP-3 REMAIN HIGH AFTER TREATMENT-INDUCED PUBERTAL ARREST IN GIRLS WITH CENTRAL PRECOCIOUS PUBERTY (CPP)
Insulin like growth factor-1 (IGF-1) increases during normal adolescence and in CPP secondary to the rise in sex steroids and GH. Treatment of CPP using GnRH analog suppresses GH as well as gonadotropins. We e...
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Article
Glyburide crosses the placenta in vivo in pregnant rats
Non-insulin-dependent diabetes mellitus (NIDDM) is normally treated by oral hypoglycaemic agents, but their use is excluded during pregnancy because of their potential teratogenic and hypoglycaemic effects on ...
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Article
Elevated serum uric acid — a facet of hyperinsulinaemia
In a representative sample of the adult Jewish population in Israel (n=1016) excluding known diabetic patients and individuals on antihypertensive medications, serum uric acid showed a positive association with p...
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Article
Effect of past and concurrent body mass index on prevalence of glucose intolerance and Type 2 (non-insulin-dependent) diabetes and on insulin response
A representative sample (n=2140) of the Israeli Jewish population aged 40–70 (excluding known diabetic patients), whose body mass index had been measured 10 years earlier, underwent an oral glucose tolerance test...
