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Fabrication and Characterization of Electrospunned Eprosartan-Loaded Biocompatible Polyvinyl Acetate/Povidone-Based Nanofiber Mat: A Novel Approach as Transdermal Carrier for Therapeutic Actives

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  1. Article

    Open Access

    Design and industrial implementation of a multi-functional part produced by powder bed fusion

    The use of robot end-effectors programmed to perform handling tasks in industrial environments has expanded in several sectors as a consequence of the rapid digital transformation seen in recent years. With su...

    A. C. Lopes, A. M. Sampaio, F. Fernandes, P. M. Vaz in Progress in Additive Manufacturing (2024)

  2. Article

    Open Access

    Resistance exercise effects on hippocampus subfield volumes and biomarkers of neuroplasticity and neuroinflammation in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial

    Physical exercise is suggested to promote hippocampal neuroplasticity by increasing circulating neurotrophic and anti-inflammatory factors. Our aim was to explore the interplay between the effect of progressiv...

    Wouter A. J. Vints, Julija Šeikinaitė, Evrim Gökçe, Simona Kušleikienė in GeroScience (2024)

  3. Article

    Open Access

    Terahertz spectroscopy of collective charge density wave dynamics at the atomic scale

    Charge density waves are wave-like modulations of a material’s electron density that display collective amplitude and phase dynamics. The interaction with atomic impurities induces strong spatial heterogeneity...

    Shaoxiang Sheng, Mohamad Abdo, Steffen Rolf-Pissarczyk, Kurt Lichtenberg in Nature Physics (2024)

  4. Article

    Correction: Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65

    A. Georgiadis, Y. Duran, J. Ribeiro, L. Abelleira-Hervas, S. J. Robbie in Gene Therapy (2024)

  5. Article

    Open Access

    Does Being In-Person Matter? Demonstrating the Feasibility and Reliability of Fully Remote Observational Data Collection

    Many conventional research methods employed in randomized controlled trials were not possible during the height of the COVID-19 pandemic. In particular, behavioral observations are nearly universally gathered ...

    Sydni A. J. Basha, Qiyue Cai, Susanne Lee, Tiffany Tran, Amy Majerle in Prevention Science (2024)

  6. Article

    Open Access

    The type III effector NopL interacts with GmREM1a and GmNFR5 to promote symbiosis in soybean

    The establishment of symbiotic interactions between leguminous plants and rhizobia requires complex cellular programming activated by Rhizobium Nod factors (NFs) as well as type III effector (T3E)-mediated sym...

    Chao Ma, **hui Wang, Yongkang Gao, Xulun Dong, Haojie Feng in Nature Communications (2024)

  7. Article

    Open Access

    Search for the \( {B}_s^0 \) → μ+μγ decay

    A search for the fully reconstructed B s 0 ...

    R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta in Journal of High Energy Physics (2024)

  8. Article

    Open Access

    Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis

    Platelet homeostasis is essential for vascular integrity and immune defence1,2. Although the process of platelet formation by fragmenting megakaryocytes (MKs; thrombopoiesis) has been extensively studied, the cel...

    Florian Gaertner, Hellen Ishikawa-Ankerhold, Susanne Stutte, Wenwen Fu in Nature (2024)

  9. Article

    Open Access

    GreatBlue: a 55-Pound Vertical-Takeoff-and-Landing Fixed-Wing sUAS for Science; Systems, Communication, Simulation, Data Processing, Payloads, Package Delivery, and Mission Flight Performance

    As small, uncrewed systems (sUAS) grow in popularity and in number, larger and larger drone aircraft will become more common–up to the FAA limit of 55 pound gross take-off weight (GTOW) and beyond. Due to thei...

    Calvin Coopmans, Stockton Slack in Journal of Intelligent & Robotic Systems (2024)

  10. Article

    Open Access

    Chronic traumatic encephalopathy (CTE) in the context of longstanding intimate partner violence

    M. Tiemensma, R. W. Byard, R. Vink, A. J. Affleck, P. Blumbergs in Acta Neuropathologica (2024)

  11. Article

    Open Access

    Pre-treatments to reduce metabolism in adult green-lipped mussel, Perna canaliculus, in preparation for live transportation

    Improved sustainability of aquaculture can be achieved by reducing product wastage post-harvest. Aquaculture of the green-lipped mussel, Perna canaliculus, is an important industry for New Zealand, which increasi...

    M. C. F. Cheng, L. N. Zamora, N. L. C. Ragg, A. J. R. Hickey in Aquaculture International (2024)

  12. Article

    Open Access

    Adherence to single inhaler triple therapy and digital inhalers in Chronic Obstructive Pulmonary Disease: a literature review and protocol for a randomized controlled trial (TRICOLON study)

    Medication non-adherence is a significant problem in patients with Chronic Obstructive Pulmonary Disease (COPD). Efforts to address this issue are receiving increased attention. Simplifying treatment by prescr...

    Liz J. A. Cuperus, Job van der Palen, Arnoud Aldenkamp in BMC Pulmonary Medicine (2024)

  13. Article

    Open Access

    Validation of the Charlson Comorbidity Index for the prediction of 30-day and 1-year mortality among patients who underwent hip fracture surgery

    The aim of our study was to validate the original Charlson Comorbidity Index (1987) (CCI) and adjusted CCI (2011) as a prediction model for 30-day and 1-year mortality after hip fracture surgery. The secondary...

    Eveline de Haan, Benthe van Oosten in Perioperative Medicine (2024)

  14. Article

    Open Access

    Experiences from patients in mental healthcare accessing their electronic health records: results from a cross-national survey in Estonia, Finland, Norway, and Sweden

    Patients’ online record access (ORA) enables patients to read and use their health data through online digital solutions. One such solution, patient-accessible electronic health records (PAEHRs) have been impl...

    A.J. Fagerlund, Annika Bärkås, A. Kharko, C.R. Blease, J. Hagström in BMC Psychiatry (2024)

  15. Article

    Open Access

    High-dimensional single-cell analysis of human natural killer cell heterogeneity

    Natural killer (NK) cells are innate lymphoid cells (ILCs) contributing to immune responses to microbes and tumors. Historically, their classification hinged on a limited array of surface protein markers. Here...

    Lucas Rebuffet, Janine E. Melsen, Bertrand Escalière in Nature Immunology (2024)

  16. Article

    Author Correction: Restoration of vision after transplantation of photoreceptors

    R. A. Pearson, A. C. Barber, M. Rizzi, C. Hippert, T. Xue, E. L. West, Y. Duran in Nature (2024)

  17. Article

    Open Access

    Surgical quality assessment of critical view of safety in 283 laparoscopic cholecystectomy videos by surgical residents and surgeons

    Surgical quality assessment has improved the efficacy and efficiency of surgical training and has the potential to optimize the surgical learning curve. In laparoscopic cholecystectomy (LC), the critical view ...

    Alexander A. J. Grüter, Freek Daams, Hendrik J. Bonjer in Surgical Endoscopy (2024)

  18. Article

    Open Access

    Altered biodistribution of [68Ga]Ga-DOTA-TOC during somatostatin analogue treatment

    The need for an interval between the administration of long-acting Somatostatin Receptor Analogues (SSA) and the [68Ga]Ga-DOTA-TATE PET has been questioned based on recent literature in the new EANM guidelines. H...

    T. van de Weijer, F. Bemer, J. de Vos-Geelen in European Journal of Nuclear Medicine and M… (2024)

  19. Article

    Open Access

    Development of a target concentration intervention to individualize paroxysmal nocturnal hemoglobinuria treatment with pegcetacoplan

    Pegcetacoplan (Aspaveli®/Empaveli™) is a factor C3 inhibitor that is approved for the treatment of paroxysmal nocturnal hemoglobinuria. An individualized dosing strategy might be useful to improve patient-frie...

    Mendy ter Avest, Saskia M.C Langemeijer, Nicole M.A. Blijlevens in Annals of Hematology (2024)

  20. Article

    Open Access

    Comparison of Clinical and Radiological Outcomes Between Different (Balloon) Guide Catheter With and Without Inflated Balloon in Acute Ischemic Stroke Patients: A MaSQ-Registry Study

    Balloon guide catheters (BGCs) are used in endovascular treatment (EVT) for ischemic stroke. Previous literature did not distinguish between BGC use with and without inflated balloon. This study aims to compar...

    R. R. M. M. Knapen, M. Celen in CardioVascular and Interventional Radiology (2024)

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