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  1. Article

    Open Access

    Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis

    Platelet homeostasis is essential for vascular integrity and immune defence1,2. Although the process of platelet formation by fragmenting megakaryocytes (MKs; thrombopoiesis) has been extensively studied, the cel...

    Florian Gaertner, Hellen Ishikawa-Ankerhold, Susanne Stutte, Wenwen Fu in Nature (2024)

  2. Article

    Open Access

    Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

    Arterial macrophages have different developmental origins, but the association of macrophage ontogeny with their phenotypes and functions in adulthood is still unclear. Here, we combine macrophage fate-map**...

    Tobias Weinberger, Dena Esfandyari, Denise Messerer, Gulce Percin in Nature Communications (2020)

  3. Article

    Open Access

    Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation

    Leukocyte-released antimicrobial peptides contribute to pathogen elimination and activation of the immune system. Their role in thrombosis is incompletely understood. Here we show that the cathelicidin LL-37 i...

    Joachim Pircher, Thomas Czermak, Andreas Ehrlich, Clemens Eberle in Nature Communications (2018)