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Open AccessPlasmacytoid dendritic cells control homeostasis of megakaryopoiesis
Platelet homeostasis is essential for vascular integrity and immune defence1,2. Although the process of platelet formation by fragmenting megakaryocytes (MKs; thrombopoiesis) has been extensively studied, the cel...
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Article
Open AccessComparison of the risk of hospital admission, need for ventilation, sepsis, pneumonitis and death among the recent monkeypox outbreak and historical outbreaks
The course of monkeypox can be severe. Our aim was to retrospectively compare the risk of hospital admission, the need for ventilation, sepsis, pneumonitis and death between the recent outbreak and historical ...
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Open AccessAuthor Correction: Vascular surveillance by haptotactic blood platelets in inflammation and infection
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Article
Open AccessVascular surveillance by haptotactic blood platelets in inflammation and infection
Breakdown of vascular barriers is a major complication of inflammatory diseases. Anucleate platelets form blood-clots during thrombosis, but also play a crucial role in inflammation. While spatio-temporal dyna...
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Article
Cellular locomotion using environmental topography
Eukaryotic cells migrate by coupling the intracellular force of the actin cytoskeleton to the environment. While force coupling is usually mediated by transmembrane adhesion receptors, especially those of the ...
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Article
Patrolling the vascular borders: platelets in immunity to infection and cancer
Platelets are small anucleate cellular fragments that are released by megakaryocytes and safeguard vascular integrity through a process termed ‘haemostasis’. However, platelets have important roles beyond haem...
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Article
68Ga-PSMA PET/CT for monitoring response to 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration-resistant prostate cancer
To evaluate the use of 68Ga-PSMA PET/CT for monitoring response to 177Lu-617 PSMA radioligand therapy in patients with metastatic castrate-resistant prostate cancer (mCRPC).
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Article
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
Although much is known about the physiological framework of T cell motility, and numerous rate-limiting molecules have been identified through loss-of-function approaches, an integrated functional concept of T...
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Article
Comparison of integrated whole-body [11C]choline PET/MR with PET/CT in patients with prostate cancer
To evaluate the performance of conventional [11C]choline PET/CT in comparison to that of simultaneous whole-body PET/MR.
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Open AccessAnti-interleukin-6 therapy for treatment of high platelet counts in cGMP-dependent protein kinase I gene-targeted mice
