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Article
Prospective study of prognostic factors in asymptomatic patients with B-cell chronic lymphocytic leukemia-like lymphocytosis: the cut-off of 11 × 109/L monoclonal lymphocytes better identifies subgroups with different outcomes
The arbitrary threshold of 5 × 109/L chronic lymphocytic leukemia (CLL)-like lymphocytes differentiates monoclonal B lymphocytosis (MBL) from CLL. There are no prospective studies that search for the optimal cut-...
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Article
Long term deformations by creep and shrinkage in recycled aggregate concrete
The main aim of this work was to determine creep and shrinkage variations experienced in recycled concrete, made by replacing the main fraction of the natural aggregate with a recycled aggregate coming from wa...
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Chapter and Conference Paper
The INTEGRAL–OMC Scientific Archive
The Optical Monitoring Camera (OMC) on-board the INTEGRAL satellite has, as one of its scientific goals, the observation of a large number of variable sources previously selected. After almost 6years of operat...
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Chapter and Conference Paper
High Energy Sources Monitored with OMC
The Optical Monitoring Camera on-board INTEGRAL (OMC) provides Johnson V band photometry of any potentially variable source within its field of view. Taking advantage of the INTEGRAL capabilities allowing the sim...
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Article
Refractory anemia with ringed sideroblasts associated with thrombocytosis: comparative analysis of marked with non-marked thrombocytosis, and relationship with JAK2 V617F mutational status
The World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues (2001) defined a provisional entity named refractory anemia with ringed sideroblasts associated to marked thro...
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Article
DNA barcoding as a tool for coral reef conservation
DNA Barcoding (DBC) is a method for taxonomic identification of animals that is based entirely on the 5′ portion of the mitochondrial gene, cytochrome oxidase subunit I (COI-5). It can be especially useful for id...
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Article
Regulation of the proapoptotic BH3-only protein BIM by glucocorticoids, survival signals and proteasome in chronic lymphocytic leukemia cells
Glucocorticoids induce apoptosis in chronic lymphocytic leukemia (CLL) cells through a caspase-dependent mechanism. However, their mechanism of action remains unknown. We have studied the regulation of the pro...
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Article
Frequency and risk factors for thrombosis in idiopathic myelofibrosis: analysis in a series of 155 patients from a single institution
Thrombosis is a frequent complication of polycythemia vera and essential thrombocythemia, but its incidence and predisposing factors in idiopathic myelofibrosis (IM) are unknown. In 18 (11.6%) of 155 patients ...
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Article
Prognostic value of minimal residual disease (MRD) in acute myeloid leukemia (AML) with favorable cytogenetics [t(8;21) and inv(16)]
Most patients with acute myeloid leukemia (AML) and t(8;21) or inv(16) have a good prognosis with current anthracycline- and cytarabine-based protocols. Tandem analysis with flow cytometry (FC) and real-time R...
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Article
Acadesine induces apoptosis in B cells from mantle cell lymphoma and splenic marginal zone lymphoma
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Article
Knee osteoarthritis: interpretation variability of radiological signs
<The aim of this study was (1) to determine the variability in detecting radiological signs of knee osteoarthritis (OA) between an orthopaedics specialist, a fourth-year resident in the speciality and a recent...
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Article
Open AccessRisk of malignant lymphoma associated with human herpesvirus-8: a case–control study in Spain
No overall increased risk of lymphoma associated with antibodies to human herpesvirus-8 was found in 526 lymphomas and 599 controls (odds ratio (OR)=1.04, 95% confidence interval (CI)=0.62–1.75); significant i...
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Article
Richter's syndrome after allogeneic stem cell transplantation for chronic lymphocytic leukaemia successfully treated by withdrawal of immunosuppression, and donor lymphocyte infusion
Development of high-grade non-Hodgkin's lymphoma is a possible complication of chronic lymphocytic leukaemia/small lymphocytic lymphoma, known as Richter's syndrome (RS). Treatment for RS includes systemic che...
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Chapter and Conference Paper
The Input Catalogue for the OMC Camera On-Board Integral
The Optical Monitoring Camera (OMC) on-board INTEGRAL (launch October 17th, 2002) has been designed to perform optical photometry simultaneously with X-ray and γ-ray observations. Due to the available RAM on t...
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Article
Lipaemia and lipoproteinaemia in a Spanish male nonsmoker population consuming sunflower oil
The aim of this study was to assess the prevalence of altered levels of serum lipids, lipoproteins and apolipoprotein (Apo) B in very active, 20 to 65 year-old, Spanish male nonsmokers who consumed sunflower o...
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Article
Granular lymphocyte proliferative disorders: A multicenter study of 20 cases
A series of 20 patients with granular lymphocyte proliferative disorders (GLPD) is reported. The criterion of inclusion was presence of persistent (≥6 months) granular lymphocytosis in the absence of any causa...
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Article
Spontaneous splenic rupture as the initial manifestation of acute lymphoblastic leukaemia: Immunophenotype and cytogenetics
Spontaneous splenic rupture is a rare, though life-threatening complication of some hematological malignancies and is even more infrequent as the initial symptom of acute lymphoblastic leukemia. We describe th...
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Article
Frozen vs. nonfrozen bone marrow for autologous transplantation in lymphomas: A report from the Spanish GEL/TAMO Cooperative Group
To investigate the impact of frozen and nonfrozen bone marrow on engraftment kinetics and disease outcome, 94 patients with non-Hodgkin's lymphoma (NHL) autografted with frozen marrow (F group) were retrospect...
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Article
Sebastian platelet syndrome
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Article
A randomized multicentric study comparing alternating combination chemotherapy (VCMP/VBAP) and melphalan-prednisone in multiple myeloma
Between January 1985 and December 1988, 386 patients with multiple myeloma were randomized to receive either MP or combination chemotherapy based on alternating cycles of VCMP and VBAP. The major prognostic pa...