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  1. No Access

    Article

    Effect of viral dose on neutralizing antibody response and transgene expression after AAV1 vector re-administration in mice

    Neutralizing antibodies (nAB) at the time of administration hamper the effectiveness of adeno-associated virus (AAV) as a clinical DNA delivery system. The present study was designed to investigate if AAV re-a...

    H Petry, A Brooks, A Orme, P Wang, P Liu, J **e, P Kretschmer, H S Qian… in Gene Therapy (2008)

  2. No Access

    Article

    Regulated expression of the interferon-β gene in mice

    A single plasmid regulated expression vector based upon a mifepristone-inducible two plasmid system, termed pBRES, has been constructed and tested in mice using murine interferon-b (mIFNb) as the transgene. Th...

    R N Harkins, P Szymanski, H Petry, A Brooks, H S Qian, C Schaefer… in Gene Therapy (2008)

  3. No Access

    Article

    Effective treatment of vascular endothelial growth factor refractory hindlimb ischemia by a mutant endothelial nitric oxide synthase gene

    Gene delivery of angiogenic growth factors is a promising approach for the treatment of ischemic cardiovascular diseases. However, success of this new therapeutic principle is hindered by the lack of critical ...

    H S Qian, P Liu, L-Y Huw, A Orme, M Halks-Miller, S M Hill, F **… in Gene Therapy (2006)