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Article
Spatial identification and evaluation of rural vitality from a function-element-flow perspective: Evidence of Lin’an district in Hangzhou, China
Rural vitality is the life force expressed by a combination of endogenous dynamics and external influences. Exploring the complex relationship between rural functions, elements and flows could achieve sustaina...
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Article
Open AccessA sensitive one-pot ROA assay for rapid miRNA detection
MicroRNAs (miRNAs) and short RNA fragments (18–25 nt) are crucial biomarkers in biological research and disease diagnostics. However, their accurate and rapid detection remains a challenge, largely due to thei...
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Article
Open AccessIn vitro and in vivo low-dose exposure of simulated cooking oil fumes to assess adverse biological effects
Cooking oil fumes (COFs) represent a major indoor environmental pollutant and exhibit potent mutagenic or carcinogenic health effects caused by containing various heterocyclic aromatic amines (HAAs) and long-c...
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Article
Function toggle of tumor microenvironment responsive nanoagent for highly efficient free radical stress enhanced chemodynamic therapy
In contrast to reactive oxygen species (ROS), the generation of oxygen-irrelevant free radicals is oxygen- and H2O2-independent in cell, which can offer novel opportunities to maximum the chemodynamic therapy (CD...
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Article
The study on in situ asymmetric bending behavior of structural bamboo materials under combined tension-bending loads
As a growing structural material in the engineering field, bamboo materials are mainly subjected to tension, bending, and a combination of the two during the service process when used as a beam structure. Howe...
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Article
Contribution of ABA metabolism and ROS generation to sugar starvation-induced senescence of rice leaves
To clarify the relationship of sugar starvation with ABA-induced ROS generation during leaf senescence, the genotype-dependent differences in sugar concentration, endogenous ABA content, and ROS generation as ...
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Article
Ultrasonic Measurement Optimization of Spot Welding Diameter of Thin Plate Based on Gain Compensation Algorithm
Aiming at the influence of signal attenuation on nugget diameter evaluation results in ultrasonic testing of resistance spot welding, a gain compensation method based on wavelet transform for different frequen...
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Article
Multiphysics simulation of the resistance spot welding detection using electromagnetic ultrasonic transverse wave
Resistance spot welding (RSW) quality substantially influences the autobody’s mechanical properties and safety performance. Nondestructive testing (NDT) method is widely used to evaluate the quality of RSW, bu...
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Article
Open AccessAssociations of ACE I/D polymorphism with the levels of ACE, kallikrein, angiotensin II and interleukin-6 in STEMI patients
This study aimed to compare the plasma levels of angiotensin-I converting enzyme (ACE), Angiotensin II (AngII), kallikrein (KLK1) and interleukin-6 (IL-6) in ST segment elevation myocardial infarction (STEMI) ...
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Article
Determination of Lignans in Schisandra sphenanthera and Schisandra chinensis Using Ionic Liquid-based Ultrasonic-assisted Extraction and High-performance Liquid Chromatography
A green, rapid and precise sample pretreatment technique, IL-based UAE(ionic liquid-based ultrasonic-assisted extraction), was coupled with high-performance liquid chromatographic separation to identify the ma...
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Protocol
Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin
Understanding the transcriptional function of thyroid hormone receptors implies a precise analysis of their interactions with chromatin and other protein components of the cells. We present here two protocols ...
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Article
Open AccessTransdifferentiation of pancreatic stromal tumor into leiomyosarcoma with metastases to liver and peritoneum: a case report
Primary pancreatic leiomyosarcoma is a rare pancreatic malignancy; the clinical presentation and treatment is not well-characterized. Further, the molecular mechanisms underlying its pathogenesis are not known...
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Article
Characteristics of patients with late manifestation of resistance thyroid hormone syndrome: a single-center experience
Resistance to thyroid hormone (RTH) is a rare genetic disease caused by reduced tissue sensitivity to thyroid hormone. The hallmark of RTH is elevated serum levels of thyroid hormone with unsuppressed thyrotr...
