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Article
Open AccessA sensitive one-pot ROA assay for rapid miRNA detection
MicroRNAs (miRNAs) and short RNA fragments (18–25 nt) are crucial biomarkers in biological research and disease diagnostics. However, their accurate and rapid detection remains a challenge, largely due to thei...
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Article
The nearly complete genome of Ginkgo biloba illuminates gymnosperm evolution
Gymnosperms are a unique lineage of plants that currently lack a high-quality reference genome due to their large genome size and high repetitive sequence content. Here, we report a nearly complete genome asse...
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Article
Open AccessA genome-wide survey of copy number variations reveals an asymmetric evolution of duplicated genes in rice
Copy number variations (CNVs) are an important type of structural variations in the genome that usually affect gene expression levels by gene dosage effect. Understanding CNVs as part of genome evolution may p...
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Article
Open AccessLRScaf: improving draft genomes using long noisy reads
The advent of third-generation sequencing (TGS) technologies opens the door to improve genome assembly. Long reads are promising for enhancing the quality of fragmented draft assemblies constructed from next-g...