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  1. Article

    Open Access

    A sensitive one-pot ROA assay for rapid miRNA detection

    MicroRNAs (miRNAs) and short RNA fragments (18–25 nt) are crucial biomarkers in biological research and disease diagnostics. However, their accurate and rapid detection remains a challenge, largely due to thei...

    Zhihao Hou, Wenpeng Deng, Alun Li, Ya Zhang, Jianye Chang, **nyue Guan in aBIOTECH (2024)

  2. No Access

    Article

    The nearly complete genome of Ginkgo biloba illuminates gymnosperm evolution

    Gymnosperms are a unique lineage of plants that currently lack a high-quality reference genome due to their large genome size and high repetitive sequence content. Here, we report a nearly complete genome asse...

    Hailin Liu, **aobo Wang, Guibin Wang, Peng Cui, Shigang Wu, Cheng Ai in Nature Plants (2021)

  3. Article

    Open Access

    A genome-wide survey of copy number variations reveals an asymmetric evolution of duplicated genes in rice

    Copy number variations (CNVs) are an important type of structural variations in the genome that usually affect gene expression levels by gene dosage effect. Understanding CNVs as part of genome evolution may p...

    Fengli Zhao, Yuexing Wang, Jianshu Zheng, Yanling Wen, Minghao Qu in BMC Biology (2020)

  4. Article

    Open Access

    LRScaf: improving draft genomes using long noisy reads

    The advent of third-generation sequencing (TGS) technologies opens the door to improve genome assembly. Long reads are promising for enhancing the quality of fragmented draft assemblies constructed from next-g...

    Mao Qin, Shigang Wu, Alun Li, Fengli Zhao, Hu Feng, Lulu Ding, Jue Ruan in BMC Genomics (2019)