24 Result(s)

Article

ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8⁺ T cells

Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...

Tu-**ong Huang, Hui-Si Huang, Shao-Wei Dong, Jia-Yan Chen… in Nature Communications (2024)

Article

Addendum: Cellular differentiation into hyphae and spores in halophilic archaea

Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova… in Nature Communications (2024)

Article

A single-cell transcriptional landscape of immune cells shows disease-specific changes of T cell and macrophage populations in human achalasia

Achalasia is a rare motility disorder of the esophagus caused by the gradual degeneration of myenteric neurons. Immune-mediated ganglionitis has been proposed to underlie the loss of myenteric neurons. Here, w...

Zu-Qiang Liu, Hao Dai, Lu Yao, Wei-Feng Chen, Yun Wang, Li-Yun Ma… in Nature Communications (2023)

Article

High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors

Single-cell nanopore sequencing of full-length mRNAs transforms single-cell multi-omics studies. However, challenges include high sequencing errors and dependence on short-reads and/or barcode whitelists. To a...

Cheng-Kai Shiau, Lina Lu, Rachel Kieser, Kazutaka Fukumura… in Nature Communications (2023)

Article

Cellular differentiation into hyphae and spores in halophilic archaea

Several groups of bacteria have complex life cycles involving cellular differentiation and multicellular structures. For example, actinobacteria of the genus Streptomyces form multicellular vegetative hyphae, aer...

Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova… in Nature Communications (2023)

Article

Continuous exposure to isoprenaline reduced myotube size by delaying myoblast differentiation and fusion through the NFAT-MEF2C signaling pathway

We aimed to explore whether superfluous sympathetic activity affects myoblast differentiation, fusion, and myofiber types using a continuous single-dose isoprenaline exposure model in vitro and to further conf...

**g Yue, Wei Xu, Li **ang, Shao-juan Chen, **n-yuan Li, Qian Yang… in Scientific Reports (2023)

Article

Identification of neuropeptides and neuropeptide receptor genes in Phauda flammans (Walker)

Neuropeptides and neuropeptide receptors are crucial regulators to insect physiological processes. The 21.0 Gb bases were obtained from Illumina sequencing of two libraries representing the female and male hea...

Hai-Pan Wu, **ao-Yun Wang, ** Hu, Ran-Ran Su, Wen Lu, **a-Lin Zheng in Scientific Reports (2022)

Article

Minor allele of rs55763075 located in MTHFR is associated with the risk of cognitive impairment after anesthesia via modulating miR-34b

This study aimed to investigate the association between cognitive impairment after general anesthesia and rs55763075 polymorphisms. We enrolled and grouped patients undergoing general anesthesia according to t...

Si-ying Li, He-shou Lei, **ao-yun Wu, Kai Li, Zhi-min Liu… in Scientific Reports (2021)

Article

Sensory gene identification in the transcriptome of the ectoparasitoid Quadrastichus mendeli

Sensory genes play a key role in the host location of parasitoids. To date, the sensory genes that regulate parasitoids to locate gall-inducing insects have not been uncovered. An obligate ectoparasitoid, Quadras...

Zong-You Huang, **ao-Yun Wang, Wen Lu, **a-Lin Zheng in Scientific Reports (2021)

Article

Author Correction: Unveiling how intramolecular stacking modes of covalently linked dimers dictate photoswitching properties

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Ru-Qiang Lu, **ao-Yun Yan, Lei Zhu, Lin-Lin Yang, Hang Qu… in Nature Communications (2020)

Article

Unveiling how intramolecular stacking modes of covalently linked dimers dictate photoswitching properties

Covalently linked π-stacked dimers represent the most significant platform for elucidating the relationship between molecular alignments and their properties. Here, we present the one-pot synthesis of two intr...

Ru-Qiang Lu, **ao-Yun Yan, Lei Zhu, Lin-Lin Yang, Hang Qu… in Nature Communications (2019)

Article

Potent Phytotoxic Harziane Diterpenes from a Soft Coral-Derived Strain of the Fungus Trichoderma harzianum XS-20090075

Two new harziane diterpene lactones, possessing a 6/5/7/5-fused carbocyclic core containing a lactone ring system, harzianelactones A and B (1 and 2), and five new harziane diterpenes, harzianones A–D (3–6) and h...

Dong-Lin Zhao, Lu-Jia Yang, Ting Shi, Chao-Yi Wang, Chang-Lun Shao… in Scientific Reports (2019)

Article

Involvement of abscisic acid-responsive element-binding factors in cassava (Manihot esculenta) dehydration stress response

Cassava (Manihot esculenta) is a major staple food, animal feed and energy crop in the tropics and subtropics. It is one of the most drought-tolerant crops, however, the mechanisms of cassava drought tolerance re...

Ren-Jun Feng, Meng-Yun Ren, Li-Fang Lu, Ming Peng, **ao Guan… in Scientific Reports (2019)

Article

Ultrafast water sensing and thermal imaging by a metal-organic framework with switchable luminescence

A convenient, fast and selective water analysis method is highly desirable in industrial and detection processes. Here a robust microporous Zn-MOF (metal–organic framework, Zn(hpi2cf)(DMF)(H₂O)) is assembled from...

Ling Chen, Jia-Wen Ye, Hai-** Wang, Mei Pan, Shao-Yun Yin… in Nature Communications (2017)

Article

Three dimensional characterization of GaN-based light emitting diode grown on patterned sapphire substrate by confocal Raman and photoluminescence spectromicroscopy

We performed depth-resolved PL and Raman spectral map**s of a GaN-based LED structure grown on a patterned sapphire substrate (PSS). Our results showed that the Raman map** in the PSS-GaN heterointerface a...

Heng Li, Hui-Yu Cheng, Wei-Liang Chen, Yi-Hsin Huang, Chi-Kang Li… in Scientific Reports (2017)

Article

A newly discovered member of the Atlastin family, BmAtlastin-n, has an antiviral effect against BmNPV in Bombyx mori

Atlastin is a member of the dynamin protein superfamily and it can mediate homotypic fusion of endoplasmic reticulum (ER) membranes, which is required for many biological processes. In this study, a new Atlast...

Tai-hang Liu, **ao-long Dong, Cai-xia Pan, Guo-yu Du, Yun-fei Wu… in Scientific Reports (2016)

Article

Investigation of an unrecognized large-scale outbreak of Candida parapsilosis sensu stricto fungaemia in a tertiary-care hospital in China

A data analysis of yeast collections from the National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) programme in 2013 revealed a sudden increase in the proportion of Candida parapsilosis complex iso...

He Wang, Li Zhang, Timothy Kudinha, Fanrong Kong, **ao-Jun Ma… in Scientific Reports (2016)

Article

A novel hepatovirus identified in wild woodchuck Marmota himalayana

Hepatitis A virus (HAV) is a hepatotropic picornavirus that causes acute liver disease worldwide. Here, we report on the identification of a novel hepatovirus tentatively named Marmota Himalayana hepatovirus (MHH...

Jie-mei Yu, Li-li Li, Cui-yuan Zhang, Shan Lu, Yuan-yun Ao… in Scientific Reports (2016)

Article

A deleterious role for Th9/IL-9 in hepatic fibrogenesis

T helper 9 (Th9) cells, a recently recognized Th cell subset, are involved in autoimmune diseases. We aimed to investigate the role of Th9/interleukin-9 (IL-9) in the pathogenesis of hepatic fibrosis. Th9 and ...

Shan-yu Qin, Dong-hong Lu, **ao-yun Guo, Wei Luo, Bang-li Hu… in Scientific Reports (2016)