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Article
Open AccessPossible step-up in prevalence for Escherichia coli ST131 from fecal to clinical isolates: inferred virulence potential comparative studies within phylogenetic group B2
Escherichia coli sequence type (ST)131 is an important urinary tract pathogen, and is responsible for considerable healthcare-associated problems and costs worldwide. A better understanding of the factors that co...
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Article
Open AccessDistribution of papG alleles among uropathogenic Escherichia coli from reproductive age women
Extraintestinal Escherichia coli (E. coli) causing urinary tract infections (UTIs), and often referred to as uropathogenic E. coli (UPEC), are a major contributor to the morbidity of UTIs and associated healthcar...
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Article
Open AccessAntimicrobial activity of omadacycline in vitro against bacteria isolated from 2014 to 2017 in China, a multi-center study
Omadacycline (ZL-2401) is a semi-synthetic derivative of minocycline. It has a broadspectrum activity against Gram-positive and Gram-negative bacteria, and atypical pathogens. The objective of this study was t...
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Article
Open AccessPrevalence of nontuberculous mycobacteria in a tertiary hospital in Bei**g, China, January 2013 to December 2018
To investigate the species distribution of non-tuberculous mycobacteria (NTM) among tuberculosis (TB) specimens collected from January 2013 to December 2018 at Peking Union Medical Hospital (Bei**g), China. N...
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Article
Open AccessFirst case report of bacteremia caused by Solobacterium moorei in China, and literature review
Solobacterium moorei, the only species in the genus Solobacterium, is a Gram-positive, non-spore-forming, strict anaerobic, short to long bacillus. It has rarely been documented to cause blood stream infections. ...
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Article
A first case of human herpesvirus-6B reactivation, confirmed by next-generation sequencing, in allopurinol-induced hypersensitivity syndrome in China
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Article
Open AccessBacteremic and non-bacteremic pneumonia caused by Acinetobacter baumannii in ICUs of South China: A Clinical and Microbiological Study
Acinetobacter baumannii has been a dreadful problem for ICU physicians for a long time. Bacteremic pneumonia (BP) caused by this organism has a higher mortality compared to other organism...
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Article
Open AccessFirst case report of endocarditis caused by haematobacter massiliensis in China
Haematobacter massiliensis, a rare species of fastidious Gram-negative, non-motile, non-sporing, non-fermentative, pleomorphic, aerobic bacilli, has rarely been documented as the cause...
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Article
Open AccessMolecular epidemiology and azole resistance mechanism study of Candida guilliermondii from a Chinese surveillance system
We studied the molecular epidemiology and mechanism of azole resistance of 164 C. guilliermondii isolates from a nationwide multi-center surveillance program. The isolates were identified by ITS gene sequencing, ...
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Article
Open AccessPrevalence of ST1193 clone and IncI1/ST16 plasmid in E-coli isolates carrying blaCTX-M-55 gene from urinary tract infections patients in China
To study molecular epidemiology of CTX-M-55-carrying Escherichia coli isolates from urinary tract infections (UTIs) in China. 111 blaCTX-M-55-positive E.coli isolates from UTIs patients in China were studied. Pul...
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Article
Open AccessUse of next generation sequence to investigate potential novel macrolide resistance mechanisms in a population of Moraxella catarrhalis isolates
Although previous studies have confirmed that 23S rRNA gene mutation could be responsible for most of macrolide resistance in M. catarrhalis, a recent study suggested otherwise. Next generation sequence based com...
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Article
Open AccessEffects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia
Stenotrophomonas maltophilia is an opportunistic pathogen that causes respiratory and urinary tract infections, as well as wound infections in immunocompromised patients. This pathogen is difficult to treat due t...
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Article
Open AccessInvestigation of an unrecognized large-scale outbreak of Candida parapsilosis sensu stricto fungaemia in a tertiary-care hospital in China
A data analysis of yeast collections from the National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) programme in 2013 revealed a sudden increase in the proportion of Candida parapsilosis complex iso...
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Article
Open AccessDiverse Genetic Background of Multidrug-Resistant Pseudomonas aeruginosa from Mainland China and Emergence of an Extensively Drug-Resistant ST292 Clone in Kunming
For a better understanding of the multidrug resistant Pseudomonas aeruginosa (MDR-PA) epidemiology in mainland China, a nationwide surveillance network of 27 tertiary hospitals was established. Non-duplicate MDR-...
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Article
Open AccessUsing a practical molecular capsular serotype prediction strategy to investigate Streptococcus pneumoniae serotype distribution and antimicrobial resistance in Chinese local hospitalized children
China is one of ten countries with the highest prevalence rate of pneumococcal infections. However, there is limited serotype surveillance data for Streptococcus pneumoniae, especially from the community or rural...
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Article
Open AccessThe First Two Clostridium difficile Ribotype 027/ST1 Isolates Identified in Bei**g, China–an Emerging Problem or a Neglected Threat?
Clostridium difficile hyper-virulent ribotype 027 strain has become a significant concern globally, but has rarely been reported in Asian countries including China. Recently, a retrospective single-center study i...
