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Article
Depleting profibrotic macrophages using bioactivated in vivo assembly peptides ameliorates kidney fibrosis
Managing renal fibrosis is challenging owing to the complex cell signaling redundancy in diseased kidneys. Renal fibrosis involves an immune response dominated by macrophages, which activates myofibroblasts in...
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Article
Open AccessSalivary proteins potentially derived from horizontal gene transfer are critical for salivary sheath formation and other feeding processes
Herbivorous insects employ an array of salivary proteins to aid feeding. However, the mechanisms behind the recruitment and evolution of these genes to mediate plant-insect interactions remain poorly understoo...
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Article
Open AccessCo-option of a non-retroviral endogenous viral element in planthoppers
Non-retroviral endogenous viral elements (nrEVEs) are widely dispersed throughout the genomes of eukaryotes. Although nrEVEs are known to be involved in host antiviral immunity, it remains an open question whe...
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Article
Safety of prone emergence from general endotracheal anesthesia in patients undergoing ERCP: a randomized controlled trial
Conventional supine emergence and prone extubation from general endotracheal anesthesia (GEA) are associated with extubation-related adverse events (ERAEs). Given the minimally invasive nature of endoscopic re...
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Article
Open AccessPlanthopper salivary sheath protein LsSP1 contributes to manipulation of rice plant defenses
Salivary elicitors secreted by herbivorous insects can be perceived by host plants to trigger plant immunity. However, how insects secrete other salivary components to subsequently attenuate the elicitor-induc...
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Article
Lipase-activated glycopeptide nano-assemblies as an antibiotic nano-adjuvant to inhibit Pseudomonas aeruginosa biofilm and enhance antibacterial activity
Bacterial infections, especially those caused by biofilms, pose a serious threat to public health. In this work, we propose a glycopeptide-based antibiotic nano-adjuvant (GalAc-2) that can synergistically enhance...
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Article
Open AccessPsychometric evaluation of an Adverse Childhood Experiences (ACEs) measurement tool: an equitable assessment or reinforcing biases?
Utilizing Adverse Childhood Experiences (ACEs) measurement scales to assess youths’ adversities has expanded exponentially in health and justice studies. However, most of the ACEs assessment scales have yet t...
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Article
CDK12 activates MYC to repress miR-28-5p/EZH2 and amplifies tonic BCR signaling to promote the development of diffuse large B-cell lymphoma
Cyclin-dependent kinase 12 (CDK12) is a transcription-associated kinase that participates in various cellular processes. However, its regulatory role in the progression of diffuse large B-cell lymphoma (DLBCL)...
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Article
Open AccessCorrection to: NLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease
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Article
Bulk properties of the medium in comparison with models’ predictions in pp collisions at 13 TeV
We report a study of the collective properties of the medium produced in pp collisions at 13 TeV. For this study, we used the measurements of the CMS experiment (Sirunyan et al. in Phys Rev D 96:112003, 2017) in ...
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Article
Reaction Behavior of Aluminogoethite and Silica Minerals in Gibbsite Bauxite in High-Temperature Digestion
The digestion behavior of silica and iron minerals in gibbsite bauxites during 230–280 °C, which has great importance for the recovery efficiency of alumina, was studied in detail in this paper. The effects of...
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Article
Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China
The potential association between maternal exposure to PM10 ranging from 3 months prior to conception to the end of the early trimester and the risk of anorectal atresia/stenosis in offspring has not been establi...
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Article
Open AccessBody composition in preschool children with short stature: a case-control study
Short stature is defined as height below 2 standard deviations of the population with the same age, gender. This study is aimed to assess the characteristics of body composition in preschool children with shor...
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Article
Open AccessA bioactivated in vivo assembly nanotechnology fabricated NIR probe for small pancreatic tumor intraoperative imaging
Real-time imaging of the tumour boundary is important during surgery to ensure that sufficient tumour tissue has been removed. However, the current fluorescence probes for bioimaging suffer from poor tumour sp...
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Article
Open AccessCorrection to: Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain
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Article
An investigation into luminescent phenoxo-bridged heterobimetallic copper(II)–calcium(II)/strontium(II)-based bis(salamo)-like complexes
Two luminescent hetero-trinuclear complexes [Cu2Ca(L)(µ2-NO3)2] (1) and [{Cu2Sr(L)(µ2-NO3)(ƞ2-NO3)}2]·2EtOH·H2O (2) have been prepared by a flexible bis(salamo)-based ligand (H4L) with Cu(NO3)·3H2O and M(OAc)2·nH
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Article
Maternal exposure to sulfur dioxide and the risk of oral clefts in Liaoning Province, China: a population-based case-control study
There is limited and equivocal epidemiological evidence relating to the association between maternal sulfur dioxide (SO2) exposure and the risk of oral clefts (OCs) in offspring. We performed a population-based c...
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Article
Open AccessChronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain
Neuroinflammation is a major driver of age-related brain degeneration and concomitant functional impairment. In patients with Alzheimer’s disease, the most common form of age-related dementia, factors that enh...
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Article
Maternal exposure to ambient SO2 and risk of polydactyly and syndactyly: a population-based case-control study in Liaoning Province, China
Evidence links exposure to maternal sulfur dioxide (SO2) and the risk of limb defects have been inconsistent. To investigate associations between SO2 exposure during preconception and the first trimester and risk...
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Article
Maternal exposure to ambient levels of sulfur dioxide and risk of neural tube defects in 14 cities in Liaoning province, China: a population-based case–control study
Epidemiological studies on the association of sulfur dioxide (SO2) with neural tube defects (NTDs) are lacking. The purpose of this study was to assess the aforementioned association through a population-based ca...
