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335 Result(s)
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Article
Open AccessAntitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4
The combination of programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) antibodies has potential for enhancing clinical efficacy. We described the development and antitumor acti...
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Open AccessSocial support, psychological capital, multidimensional job burnout, and turnover intention of primary medical staff: a path analysis drawing on conservation of resources theory
Job burnout is a prevalent and emerging challenge in the primary medical system, causing mass turnover, especially of primary medical staff. Little attention has been paid to the different dimensions of job bu...
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Upregulation of eIF2α by m6A modification accelerates the proliferation of pulmonary artery smooth muscle cells in MCT-induced pulmonary arterial hypertension rats
Pulmonary arterial hypertension (PAH) is a malignant cardiovascular disease. Eukaryotic initiation factor 2α (eIF2α) plays an important role in the proliferation of pulmonary artery smooth muscle cells (PASMCs...
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Open AccessBehavioral and social drivers of COVID-19 vaccination initiation in the US: a longitudinal study March─ October 2021
Many studies have examined behavioral and social drivers of COVID-19 vaccination initiation, but few have examined these drivers longitudinally. We sought to identify the drivers of COVID-19 vaccination initia...
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Open AccessNeurofibromatosis type 1 with huge intrathoracic meningoceles misdiagnosed as pleural effusion: A case report and literature review
Neurofibromatosis type 1 is a genetic disease that affects multiple organs and systems, leading to various clinical manifestations. In Neurofibromatosis type 1, rare intrathoracic meningoceles often occur alon...
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Article
Super P and MoO2/MoS2 co-doped gradient nanofiber membrane as multi-functional separator for lithium–sulfur batteries
Lithium–sulfur battery is one of the most promising battery systems for industrialization due to its high theoretical specific capacity and high energy density. Nonetheless, the “shuttle effect” has restrained...
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Open AccessSingle-cell and spatial transcriptomics reveal metastasis mechanism and microenvironment remodeling of lymph node in osteosarcoma
Osteosarcoma (OS) is the most common primary malignant bone tumor and is highly prone to metastasis. OS can metastasize to the lymph node (LN) through the lymphatics, and the metastasis of tumor cells reestabl...
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Article
A novel phasor-based adaptive single-phase auto-reclosing scheme for transmission lines with shunt reactors
A novel adaptive single-phase auto-reclosing method is proposed, which utilizes the internal product ratio of mode voltage to accurately determine the fault natures and the secondary arc extinction time of hig...
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Article
Discrete-Velocity-Direction Models of BGK-Type with Minimum Entropy: II—Weighted Models
In this series of works, we develop a discrete-velocity-direction model (DVDM) with collisions of BGK-type for simulating gas flows, where the molecular motion is confined to some prescribed directions but the...
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Article
The role of exposure condition, awareness and item type in develo** implicit and explicit knowledge of collocational rules
This study expands on previous SLA research by focusing on learning collocational rules. The study also explores the interaction between exposure conditions, awareness, and item-related variables in the contex...
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Article
Open AccessPhysical breakdown of CH4 hydrate under stress: a molecular dynamics simulation study
As a solid energy source, CH4 hydrate will inevitably break down physically as the result of geological movement or exploitation. Here, the molecular dynamics method was employed to simulate the uniaxial-deformat...
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Open AccessVisual function loss in fungal sphenoid sinusitis: clinical characteristics and outcomes
Potentially fatal fungal sphenoid sinusitis (FSS) causes visual damage. However, few studies have reported on its visual impairment and prognosis. Five hundred and eleven FSS patients with ocular complications...
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Open AccessAge and mean platelet volume-based nomogram for predicting the therapeutic efficacy of metoprolol in Chinese pediatric patients with vasovagal syncope
Vasovagal syncope (VVS) is the most common type of orthostatic intolerance in children. We investigated whether platelet-related factors related to treatment efficacy in children suffering from VVS treated wit...
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Open AccessNardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) develops through step-wise genetic and molecular alterations including Kras mutation and inactivation of various apoptotic pathways. Here, we find that development of ap...
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Evaluating variations in the barriers to colorectal cancer screening associated with telehealth use in rural U.S. Pacific Northwest
The incidence and mortality rates of colorectal cancer (CRC) remain consistently high in rural populations. Telehealth can improve screening uptake by overcoming individual and environmental disadvantages in r...
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Article
Prelacrimal recess approach for maxillary sinus inverted papilloma: a 15-year experience from a single center
This large retrospective, single-center, follow-up study investigated the endoscopic prelacrimal recess approach (PLRA) for treating maxillary sinus inverted papilloma (MSIP).
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Open AccessPhosphonate-based iron complex for a cost-effective and long cycling aqueous iron redox flow battery
A promising metal-organic complex, iron (Fe)-NTMPA2, consisting of Fe(III) chloride and nitrilotri-(methylphosphonic acid) (NTMPA), is designed for use in aqueous iron redox flow batteries. A full-cell testing, w...
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Root system architecture change in response to waterlogging stress in a 448 global collection of rapeseeds (Brassica napus L.)
A novel image-based screening method for precisely identifying genotypic variations in rapeseed RSA under waterlogging stress was developed. Five key root traits were confirmed as good indicators of waterloggi...
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Open AccessA study on the impact of marital status on the survival status of prostate cancer patients based on propensity score matching
Marital status is an independent prognostic factor for survival in many types of cancers, but its prognostic impact on patients with prostate cancer (PCa) has not been established. The aim of this study was to...
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Article
Adaptive video stabilization based on feature point detection and full-reference stability assessment
Video stabilization is an important video enhancement technique that removes shaky motion and produces stable videos with good visual quality. Previous feature point matching methods are proposed to estimate m...