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  1. Article

    Open Access

    Integrated multi-omics analyses revealed the association between rheumatoid arthritis and colorectal cancer: MYO9A as a shared gene signature and an immune-related therapeutic target

    Our study aims to explore the relationship, shared gene signature, and the underlying mechanisms that connect rheumatoid arthritis (RA) to colorectal cancer (CRC).

    Zhi-Qing Zhan, Ze-Min Huang, Qi-Wen Lan, Yu-Hua Luo, Jia-**n Li in BMC Cancer (2024)

  2. Article

    Open Access

    Global research hotspots, development trends and prospect discoveries of phase separation in cancer: a decade-long informatics investigation

    Liquid-liquid phase separation (LLPS) is a complex and subtle phenomenon whose formation and regulation take essential roles in cancer initiation, growth, progression, invasion, and metastasis. This domain hol...

    Song-Bin Guo, Xue-Zhao Feng, Wei-Juan Huang, Zhen-Zhong Zhou in Biomarker Research (2024)

  3. Article

    Open Access

    Efficacy and safety of cladribine, low-dose cytarabine and venetoclax in relapsed/refractory acute myeloid leukemia: results of a pilot study

    Yan-Yan Li, Shuai-Shuai Ge, Yuan-Hong Huang, Ming-Zhu Xu in Blood Cancer Journal (2024)

  4. No Access

    Article

    Molecular classification of hormone receptor-positive HER2-negative breast cancer

    Hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2) breast cancer is the most prevalent type of breast cancer, in which endocrine therapy resistance and distant relapse remai...

    ** **, Yi-Fan Zhou, Ding Ma, Shen Zhao, Cai-** Lin, Yi **ao, Tong Fu in Nature Genetics (2023)

  5. No Access

    Article

    The SLITRK4-CNPY3 axis promotes liver metastasis of gastric cancer by enhancing the endocytosis and recycling of TrkB in tumour cells

    Gastric cancer (GC) is a malignant tumour with high mortality, and liver metastasis is one of the main causes of poor prognosis. SLIT- and NTRK-like family member 4 (SLITRK4) plays an important role in the ner...

    Yao-Qi Zhou, Tian-Shang Bao, Jia-Xuan **e, Lin-Li Yao, Si-Te Yu in Cellular Oncology (2023)

  6. Article

    Open Access

    Impact of posttransplant cyclophosphamide on the outcome of patients undergoing unrelated single-unit umbilical cord blood transplantation for pediatric acute leukemia

    Umbilical cord blood transplantation (UCBT) from unrelated donors is one of the successful treatments for acute leukemia in childhood. The most frequent side effect of UCBT is peri-engraftment syndrome (PES), ...

    **n-Yu Li, Li-** Zhan, Dian-Dian Liu, **a-Wei Han, Han Chen, Zheng-Zhou Wu in BMC Cancer (2022)

  7. Article

    Open Access

    HDAC4 promotes the growth and metastasis of gastric cancer via autophagic degradation of MEKK3

    Histone deacetylases (HDACs) have been shown to be involved in tumorigenesis, but their precise role and molecular mechanisms in gastric cancer (GC) have not yet been fully elucidated.

    Wei-Jie Zang, Yi-Lin Hu, Chen-Yu Qian, Ying Feng, Jia-Zhou Liu in British Journal of Cancer (2022)

  8. No Access

    Article

    SunUp and Sunset genomes revealed impact of particle bombardment mediated transformation and domestication history in papaya

    Transgenic papaya is widely publicized for controlling papaya ringspot virus. However, the impact of particle bombardment on the genome remains unknown. The transgenic SunUp and its progenitor Sunset genomes w...

    **g**g Yue, Robert VanBuren, Juan Liu, **g** Fang, **ngtan Zhang in Nature Genetics (2022)

  9. Article

    Open Access

    Genomic features of rapid versus late relapse in triple negative breast cancer

    Triple-negative breast cancer (TNBC) is a heterogeneous disease and we have previously shown that rapid relapse of TNBC is associated with distinct sociodemographic features. We hypothesized that rapid versus ...

    Yiqing Zhang, Sarah Asad, Zachary Weber, David Tallman, William Nock in BMC Cancer (2021)

  10. Article

    Antibody responses to SARS-CoV-2 in patients with COVID-19

    We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG...

    Quan-**n Long, Bai-Zhong Liu, Hai-Jun Deng, Gui-Cheng Wu, Kun Deng in Nature Medicine (2020)

  11. No Access

    Article

    Wang et al. reply

    Pi-**ao Wang, Guang-Nian Zhao, Yan-**ao Ji, Peng Zhang, **ao-**g Zhang in Nature Medicine (2018)

  12. Article

    Open Access

    Medical expenses of urban Chinese patients with stomach cancer during 2002–2011: a hospital-based multicenter retrospective study

    In China, stomach cancer is the third most common cancer and the third leading cause of cancer death. Few studies have examined Chinese stomach cancer patients’ medical expenses and their associated trends. Th...

    **ao-Jie Sun, Ju-Fang Shi, Lan-Wei Guo, Hui-Yao Huang, Neng-Liang Yao in BMC Cancer (2018)

  13. Article

    Open Access

    Signaling protein signature predicts clinical outcome of non-small-cell lung cancer

    Non-small-cell lung cancer (NSCLC) is characterized by abnormalities of numerous signaling proteins that play pivotal roles in cancer development and progression. Many of these proteins have been reported to b...

    Bao-Feng **, Fan Yang, **ao-Min Ying, Lin Gong, Shuo-Feng Hu, Qing Zhao in BMC Cancer (2018)

  14. Article

    Open Access

    Long-term survival analysis in combined transarterial embolization and stereotactic body radiation therapy versus stereotactic body radiation monotherapy for unresectable hepatocellular carcinoma >5 cm

    The survival following transarterial chemoembolization (TACE) alone is still low in unresectable hepatocellular carcinoma (HCC) with almost patients develo** disease progression after treatment. There is nee...

    Ting-Shi Su, Huan-Zhen Lu, Tao Cheng, Ying Zhou, Yong Huang, Ying-Chuan Gao in BMC Cancer (2016)

  15. Article

    Open Access

    Cancer incidence in urban Shanghai, 1973-2010: an updated trend and age-period-cohort effects

    To provide a comprehensive overview of temporal trends in cancer incidence during 1973–2010 in urban Shanghai.

    **-** Bao, Ying Zheng, Chun-**ao Wu, Zhe-Zhou Huang, Yu-Tang Gao, Fan ** in BMC Cancer (2016)

  16. Article

    Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

    Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan ** in Nature Genetics (2014)

  17. No Access

    Article

    Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

    Dongxin Lin, Philip Taylor, Li-Dong Wang and colleagues have now pooled three genome-wide association analyses of esophageal squamous cell carcinoma, finding two new risk loci at genome-wide significance and a...

    Chen Wu, Zhaoming Wang, **n Song, **ao-Shan Feng, Christian C Abnet in Nature Genetics (2014)

  18. Article

    Open Access

    Radiation-induced temporal lobe injury after intensity modulated radiotherapy in nasopharyngeal carcinoma patients: a dose-volume-outcome analysis

    To identify the radiation volume effect and significant dosimetric parameters for temporal lobe injury (TLI) and determine the radiation dose tolerance of the temporal lobe (TL) in nasopharyngeal carcinoma (NP...

    Ying Sun, Guan-Qun Zhou, Zhen-Yu Qi, Li Zhang, Shao-Min Huang, Li-Zhi Liu in BMC Cancer (2013)

  19. No Access

    Article

    Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

    Long Yu and colleagues report a genome-wide association study for hepatitis B virus–related hepatocellular carcinoma (HBV-HCC). They report that genetic variants in STAT4 and HLA-DQ genes confer risk of HBV-HCC.

    De-Ke Jiang, Jielin Sun, Guangwen Cao, Yao Liu, Dongxin Lin, Yu-Zhen Gao in Nature Genetics (2013)

  20. Article

    Open Access

    PRAF3 induces apoptosis and inhibits migration and invasion in human esophageal squamous cell carcinoma

    Prenylated Rab acceptor 1 domain family member 3 (PRAF3) is involved in the regulation of many cellular processes including apoptosis, migration and invasion. This study was conducted to investigate the effect...

    Guo-Zhen Shi, Yang Yuan, Guo-Jun Jiang, Zhi-Jun Ge, Jian Zhou, De-Jun Gong in BMC Cancer (2012)

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