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Article

HDAC4 promotes the growth and metastasis of gastric cancer via autophagic degradation of MEKK3

Histone deacetylases (HDACs) have been shown to be involved in tumorigenesis, but their precise role and molecular mechanisms in gastric cancer (GC) have not yet been fully elucidated.

Wei-Jie Zang, Yi-Lin Hu, Chen-Yu Qian, Ying Feng, Jia-Zhou Liu… in British Journal of Cancer (2022)