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  1. No Access

    Chapter and Conference Paper

    Role of Serum Lipoproteins in the Transport of Cellular Cholesterol

    The subject of this presentation is the role of serum lipoproteins in the transport of cellular cholesterol. The donors of cellular cholesterol originate mostly in the liver and the pathways of their synthesis...

    Y. Stein, O. Stein, J. Vanderhoek in Lipoprotein Metabolism (1976)

  2. No Access

    Chapter and Conference Paper

    Effects of Low Dose Phytosterols on Cholesterol Absorption in Man

    The plasma cholesterol lowering action of phytosterols has been known for many years (1 – 3). It has generally been thought that large doses of phytosterols are required to obtain a significant reduction in pl...

    S. M. Grundy, H. Y. I. Mok in Lipoprotein Metabolism (1976)

  3. No Access

    Chapter and Conference Paper

    Sitosterol in Type II Hyperlipoproteinemia

    In 1951, PETERSON reported that the increase of plasma cholesterol levels in chickens caused by cholesterol feeding can be prevented by including 1 % soybean sterols in the diet (18). Since then, numerous inve...

    P. Oster, G. Schlierf, C. Heuck, H. Greten, U. Gundert-Remy… in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    Human Postheparin Plasma Lipolytic Activities

    Human postheparin lipolytic activities (PHLA) are considered to bemajor factors in the removal of triglycerides from circulating plasma lipoproteins (1). It was assumed, that this glycerol ester hydrolase acti...

    J. Augustin, H. Freeze, J. Boberg, W. V. Brown in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    Molecular Association of Lipids and Proteins in the Plasma Lipoproteins: A Review

    In blood, the plasma lipoproteins represent the major vehicle for the transport of triglyceride, cholesterol, both free and esterified, and phospholipid. In addition, these macromolecular complexes are also su...

    A. M. Gotto, R. L. Jackson Jr., J. D. Morrisett, H. J. Pownall… in Lipoprotein Metabolism (1976)

  6. No Access

    Chapter and Conference Paper

    Reversible Activation-Deactivation of Hormone-Sensitive Lipase and Observations on its Relation to Lipoprotein Lipase

    The rate of release of free fatty acids (FFA) from adipose tissue is stimulated by catecholamines, glucagon, ACTH, and many other so-called lipolytic hormones.The increase in FFA release from intact tissue cor...

    D. Steinberg, J. C. Khoo in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    Metabolism of Very Low Density Lipoproteins

    The plasma lipoprotein system is traditionally separated into several lipoprotein families defined by physical, chemical, and immunochemical methods. Yet, during the last few years, it has been shown that all ...

    S. Eisenberg in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    The Composition, Structure, and Metabolism of High Density Lipoprotein

    The purpose of this report is to review recent advances in the understanding of high density lipoprotein (HDL) composition, structure, and metabolism. HDL appears to serve as a carrier for cholesterol, mainly ...

    R. I. Levy, C. B. Blum, E. J. Schaefer in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    Lipid Composition of the Major Human Serum Lipoprotein Density Classes in Different Types of Hyperlipoproteinemia

    The six types of hyperlipoproteinemia recognized in the WHO memorandum (1) are based upon criteria that take into consideration the concentration of very low density (VLDL) and low density (LDL) lipoproteins.T...

    L. A. Carlson in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    Binding, Uptake, and Catabolism of Low Density (LDL) and High Density Lipoproteins (HDL) by Cultured Smooth Muscle Cells

    Over the past several years our laboratory has concerned itself with the sites of removal and degradation of plasma low density lipoproteins (LDL) and the cellular mechanisms involved. In vivo studies in dogs ...

    D. Steinberg, T. E. Carew, D. B. Weinstein, T. Koschinsky in Lipoprotein Metabolism (1976)

  11. No Access

    Chapter and Conference Paper

    Structure-Function Relationships of Lipoproteins in Tangier Disease

    Tangier disease is a rare diserder ef plasma lipid transpert theught to. be due to. a mutant autesemal gene. The disease was discevered in 1960 (1 – 3) and given its name frem Tangier Island which lies eff the...

    G. Assmann in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    Effects of Sitosterol Therapy on Plasma Lipid and Lipoprotein Concentrations

    The ideal drug for the treatment of hypercholesterolemia should be effective, free of subjective side-effects and of objective toxicity. The cholesterol analog, beta-sitosterol (Fig. 1), comes close to that id...

    R. S. Lees, Ann M. Lees in Lipoprotein Metabolism (1976)

  13. No Access

    Chapter and Conference Paper

    Lipases and Lipoproteins

    The degradation of triglyceride-rich plasma lipoproteins and the uptakeof their lipid constituents by tissues is dependent on enzymaticactivities which reside on or near the luminal surface of the capillary en...

    W. V. Brown, W. Shaw, M. Baginsky, J. Boberg, J. Augustin in Lipoprotein Metabolism (1976)

  14. No Access

    Chapter and Conference Paper

    Carbon 13 Nmr-Spectroscopic Studies on Liposomes and Human high Density Lipoproteins

    Complex lipids have been recognized to be closely related to the main functions of a membrane:

    1. Barrier function, which is solely depen...

    W. Stoffel in Lipoprotein Metabolism (1976)

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    Chapter and Conference Paper

    Physiologic Implications of the Interaction between Lipoprotein Lipase and Some Sulfated Glycosaminoglycans

    Lipoprotein lipase was first detected in postheparin plasma. However, it is now clear that the main physiologic site of action of this enzyme is not in the circulating blood but at the capillary endothelium. H...

    T. Olivecrona, G. Bengtsson, M. Höök, U. Lindahl in Lipoprotein Metabolism (1976)

  16. No Access

    Chapter and Conference Paper

    Recent Studies of the Role of the Lecithin-Cholesterol Acyltransferase Reaction in Plasma Lipoprotein Metabolism

    Our group1 has been investigating the role of the lecithin-cholesterol acyltransferase (LCAT) reaction in plasma lipoprotein metabolism by studying the plasma lipoproteins of patiepts with familial LCAT deficienc...

    J. A. Glomset in Lipoprotein Metabolism (1976)

  17. No Access

    Chapter and Conference Paper

    Low Density Lipoprotein Metabolism and Cholesterol Synthesis in Familial Homozygous Hypercholesterolemia: Influence of Portacaval Shunt Surgery

    Several recent studies of patients with the homozygous form of familial hypercholesterolemia (FH) have provided new insight into mechanisms underlying the elevation of plasma low density lipoprotein (LDL) in t...

    D. W. Bilheimer in Lipoprotein Metabolism (1976)

  18. No Access

    Chapter and Conference Paper

    Metabolism of Lipid and Protein Components of Triglyceride-Rich Lipoproteins in Rats and Humans

    The pseudomicellar (apolar core, polar surface-shell) model for spherical lipoproteins occurring in normal blood plasma provides a useful framework for evaluating the metabolism of the various lipid and protei...

    R. J. Havel, J. P. Kane, A. Pagnan in Lipoprotein Metabolism (1976)

  19. No Access

    Chapter and Conference Paper

    Role of the LDL Receptor in the Regulation of Cholesterol and Lipoprotein Metabolism

    Although it has been well documented that nonhepatic tissues uniformly exhibit low rates of cholesterol synthesis (1, 2), the factors responsible for this suppression and the enzymatic site of regulation have ...

    M. S. Brown, K. Luskey, H. A. Bohmfalk, J. Helgeson… in Lipoprotein Metabolism (1976)

  20. No Access

    Chapter and Conference Paper

    Introduction to Chronobiology

    Recorded recognition of the importance of biological rhythms in plants and animals dates back at least to 5000 b.c. Over the years, the understanding of rhythmic phenomena has grown, but the acceptance of chronob...

    Alain Reinberg, Michael H. Smolensky in Biological Rhythms and Medicine (1983)

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