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Article
Open AccessComparison of visceral fat mass measurement by dual-X-ray absorptiometry and magnetic resonance imaging in a multiethnic cohort: the Dallas Heart Study
Visceral adipose tissue (VAT) mass, a risk factor for cardiometabolic complications of obesity, is usually measured by magnetic resonance imaging (MRI) but this method is not practical in a clinical setting. I...
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Article
Adipose tissue mass and location affect circulating adiponectin levels
Plasma levels of adiponectin are inversely associated with body mass. We hypothesised that adipose tissue distribution and body composition influences adiponectin levels.
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Chapter
Metabolic Syndrome: Therapeutic Considerations
The metabolic syndrome is a constellation of metabolic risk factors for atherosclerotic cardiovascular disease (ASCVD) occurring in one individual. There are five cardiovascular risk factors that accompany the...
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Chapter and Conference Paper
Familial Combined Hyperlipidemia Workshop
On April 17 and 18, 1986, a workshop on familial combined hyperlipidemia was held at the Battelle Conference Center, Seattle, Washington. The term familial combined hyperlipidemia (FCHL) was first used by Joseph ...
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Chapter and Conference Paper
Bile Acid Sequestrants: Do They Have a Future?
It has been known for many years that interruption of the enterohepatic circulation (EHC) of bile acids will lower the plasma cholesterol. Interruption of the EHC can be achieved in several ways, but the usual...
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Chapter and Conference Paper
Dietary Lecithin: Metabolism, Fate, and Effects on Metabolism of Lipids and Lipoproteins
The phospholipids, of which lecithin is a major component, constitute a major class of lipids in body tissues and in plasma. They play a vital role in cellular function and in transport of lipids. Since they a...
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Chapter
Evaluation of the clinical significance of the discovery of the LDL receptor
Over a decade ago, Goldstein and Brown [1] discovered the cell-surface receptor for low density lipoprotein (LDL). Since this discovery, these investigators and their co-workers have defined the structure, ori...
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Chapter
Metabolic factors in pathogenesis of cholesterol gallstones: implications for gallstone prevention
Current treatment of clinical gallstone disease is generally successful. Cholecystectomy carries a low mortality and usually effects a complete cure. The recent introduction of pharmacological dissolution of c...
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Chapter and Conference Paper
Contribution of Apoprotein B Production Rate in the Regulation of Lipoprotein Levels in Man
There is a wide range in plasma total and low density lipoprotein (LDL) cholesterol in the general population, but factors determining this variability are poorly understood. The work of Goldstein and Brown (1) h...
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Chapter and Conference Paper
Symposium Drugs Effecting Cholesterol Disposition
Levels of plasma lipoproteins are regulated by the balance between their production and clearance. Although great attention has been paid to mechanisms for clearance of lipoproteins from plasma, work on factor...
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Article
Very low density lipoprotein metabolism in non-ketotic diabetes mellitus: Effect of dietary restriction
We have measured the turnover of very low density lipoprotein (VLDL) triglyceride as well as plasma glucose, insulin and non-esterified fatty acid levels in nine mildly obese non-ketotic, insulinopenic diabeti...
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Chapter and Conference Paper
Synthese von Cholesterin, Gallensäuren und VLDL-Triglyceriden bei familiärer kombinierter Hyperlipidämie
Die familiäre kombinierte Hyperlipidämie (FKHL) ist eine autosomal dominant vererbte Fettstoffwechselstörung, die 1973 von drei Arbeitsgruppen in den USA und Europa unabhängig voneinander beschrieben wurde. Di...
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Chapter and Conference Paper
Effects of Low Dose Phytosterols on Cholesterol Absorption in Man
The plasma cholesterol lowering action of phytosterols has been known for many years (1 – 3). It has generally been thought that large doses of phytosterols are required to obtain a significant reduction in pl...
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Chapter and Conference Paper
Workshop: Management of Hyperlipoproteinemias with Non-Absorbable Drugs
The workshop in the management of atherosclerosis was concerned with non-absorb-able drugs. These agents act within the intestinal lumen interfering with cholesterol and bile acid absorption. The resulting enh...
