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Vital METS/MIRAI
Dysregulation of microRNAs (miRNAs) has been implicated in human disease. Further, a panel of vital circulating microRNA has also been involved in...
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Diabetes Mellitus: Quantum MicroRNA Language with Artificial Intelligence (MIRAI) as an Early Diagnostic Tool for Type 2 Diabetes Mellitus for Sustainable Healthcare
Circulating miRNA profiles have long been analyzed as noninvasive biomarkers of metabolic diseases. However, the results of most miRNA biomarker...
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Matrix Multiplication for MicroRNA Qubit
MicroRNA (miRNA) sequences were converted into miRNA qubits according to Schröedinger’s wave equation. Cohered interactions between two miRNA qubits...
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Etiology Analysis for Human Cancer
Although disease prediction by microRNAs (miRNAs) based on mathematical data science has been statistically validated, no disease prediction can...
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Metabolic Disease and Alzheimer’s Disease
Age-related diseases (ARDs) include inflammatory atherosclerosis and cardiovascular disease in coronary artery disease (CAD), hypertension, type 2...
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RNA Controls RNA
We know that microRNAs (miRNAs) are ubiquitous in all organisms. On the contrary, proteins are encoded in DNA on the genome and transcribed into...
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MicroRNA Qubit
We use Schröedinger’s wave equation to show that it is possible to work with physical transformations from microRNA (miRNA) information. Quantum...
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Encounter with the Unknown
The severe respiratory syndrome human coronavirus 2 (SARS-CoV-2) pandemic has forced us to recognize the need for rapid analysis of unknown viral...
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MiRNA Immunity Against Virus and MiRNA Surveillance Against Tumor
Through the microRNA (miRNA) entangling target sorting/quantum miRNA language plus artificial intelligence (METS/MIRAI) analysis so far, it seems...
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MicroRNA Quantum Computing
Due to the multiple targets of microRNA (miRNA) and messenger RNA (mRNA) interactions and the complexity of protein/protein interactions, the...
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Thyroid Cancer: Quantum MicroRNA Language/Artificial Intelligence (MIRAI)-Based Etiologic Analysis of Thyroid Cancer by Serum/Plasma miRNA Panel Data
We have previously demonstrated that cancer pathogenesis can be simulated in silico by using a panel of circulating microRNAs (miRNAs) as biomarkers....
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Quantum MiRNA Code
The C. elegans’s lin-4 discovery in 1993 to date are still limited to C. elegans-specific RNA interference. The function of microRNA (miRNA) is based...
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Metabolic Profile of Adaptive Immune Cells
Recently, evidence derived from different studies has shown that metabolic routes determine the fate of immune cells and impact the immune response,...
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Metabolic Reprogramming and Cancer
Cancer cell metabolism reprograming has been investigated for many years. What started with the idea that cancer cells had respiratory deficiencies...
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Mitochondrial Biogenesis and Dynamics in Health and Disease
Mitochondria control a myriad of intracellular processes including ATP synthesis, redox balance, ion homeostasis and metabolism of amino acids and...
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Visualizing Effector Triggered Immunity in Response to Pore-Forming Toxins by Live-Cell Imaging
The NLRP3 inflammasome senses the activity of pore-forming toxins secreted by Staphylococcus aureus. The bacterial toxins compromise plasma membrane...
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A Brief Introduction to Effector-Triggered Immunity
Detection of microbes by the host is essential to restrict microbial colonization, to clear pathogens, and to mount adapted defense reactions, and...
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Quantifying Regulated Mitochondrial Fission in Macrophages
Mitochondria have co-evolved with eukaryotic cells for more than a billion years, becoming an important cog in their machinery. They are best known...
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Time-Resolved Fluorescence Microscopy Screens on Host Protein Subversion During Bacterial Cell Invasion
Intracellular bacterial pathogens have evolved a plethora of strategies to invade eukaryotic cells. By manipulating host signaling pathways, in...
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Detection of Gasdermin Activation and Lytic Cell Death During Pyroptosis and Apoptosis
Cytosolic pattern recognition receptors trigger pyroptosis by detection of danger- or pathogen-associated molecular patterns. These receptors...