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    Chapter

    Circumvention of Neoplastic Heterogeneity by Systemically Activated Macrophages

    The continuous growth of metastases that are resistant to conventional therapies is the major cause of death from colorectal carcinoma. Recent data indicate that metastases can arise from the nonrandom spread ...

    Isaiah J. Fidler, J. Milburn Jessup… in Biology and Treatment of Colorectal Cancer… (1986)

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    Chapter

    Role of Macrophages in Host Resistance Against Tumors

    The most devastating aspect of cancer is the propensity of malignant neoplasms to spread from their primary site of growth to distant organs where secondary tumors, metastases, can develop. Despite remarkable ...

    William E. Fogler, Isaiah J. Fidler in Basic and Clinical Tumor Immunology (1983)