33 Result(s)
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Chapter
Qi** Li
Biomedicine
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Chapter
Correction to: Therapeutics and Diagnostics Discovery
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Chapter
Animal Models of Tuberculosis
Tuberculosis (TB) is an important zoonotic disease caused by infection with Mycobacterium tuberculosis (Mtb) complex and has a significant impact on public health. Animal models are suitable tools to mimic the cl...
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Nanomechanics of Aggrecan: A New Perspective on Cartilage Biomechanics, Disease and Regeneration
Articular cartilage is a hydrated macromolecular composite mainly composed of type II collagen fibrils and the large proteoglycan, aggrecan. Aggrecan is a key determinant of the bearing and energy dissipatio...
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Advances in Development of mRNA-Based Therapeutics
Recently, mRNA-based therapeutics have been greatly boosted since the development of novel technologies of both mRNA synthesis and delivery system. Promising results were showed in both preclinical and clinica...
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Chapter and Conference Paper
Resting-State fMRI Investigation in Patients with Cervical Spondylotic Myelopathy
Cervical spondylotic myelopathy (CSM) is a common degenerative neurological disorder, usually influence on the walking ability with balance problem. The balance control during walking is a problem of motor and...
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Correction to: The Use of Botulinum Toxin for Treatment of Spasticity
The chapter was inadvertently published without a more specific title according to SEO guidelines. A chapter title needs to be understandable when seen as a stand-alone item, e.g. on PubMed. The chapter title ...
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Optical Redox Imaging Differentiates Triple-Negative Breast Cancer Subtypes
Triple-negative breast cancer (TNBC) is a highly diverse group of cancers with limited treatment options, responsible for about 15% of all breast cancers. TNBC cells differ from each other in many ways such as...
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Glutamine Metabolism in Cancer
Metabolism is a fundamental process for all cellular functions. For decades, there has been growing evidence of a relationship between metabolism and malignant cell proliferation. Unlike normal differentiated ...
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Amino Acid Nutrition and Metabolism in Chickens
Both poultry meat and eggs provide high-quality animal protein [containing sufficient amounts and proper ratios of amino acids (AAs)] for human consumption and, therefore, play an important role in the growth,...
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Asthma and Autophagy
Asthma is one of the most common diseases of the respiratory system, with typical pathogenesis and pathological changes. The current research shows that autophagy is mainly involved in the pathogenesis of asth...
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The Discovery Process of SFTS in China
Heightened surveillance of acute febrile illness in China since 2004 led to the identification of a severe fever with thrombocytopenia syndrome (SFTS) with unknown etiology. Sporadic patients hospitalized with...
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Application of UPT-POCT in Public Health Emergencies
Rapid and reliable detection of infectious agents on site is essential for timely initiation of medical treatment and post-exposure prophylactic measures when public health emergencies occur. However, the refe...
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Roles of Drug Transporters in Blood-Retinal Barrier
Blood-retinal barrier (BRB) includes inner BRB (iBRB) and outer BRB (oBRB), which are formed by retinal capillary endothelial (RCEC) cells and by retinal pigment epithelial (RPE) cells in collaboration with Br...
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Correction to: Echinodermata: The Complex Immune System in Echinoderms
Correction to: Chapter 13 in: E. L. Cooper (ed.), Advances in Comparative Immunology, https://doi.org/10.1007/978-3-319-76768-0_13
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Engineering Antibodies for the Treatment of Infectious Diseases
Historically, serum therapy was previously used to combat infectious pathogens. However, serum sickness and anaphylaxis limited its broad application. The advancement of antibody engineering technologies has m...
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Chapter and Conference Paper
The Relative Contributions of Temporal Envelope and Fine Structure to Mandarin Lexical Tone Perception in Auditory Neuropathy Spectrum Disorder
Previous studies have demonstrated that temporal envelope (E) is sufficient for speech perception, while fine structure (FS) is important for pitch perception for normal-hearing (NH) listeners. Listeners with ...
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Flow of Information Underlying a Tactile Decision in Mice
Motor planning allows us to conceive, plan, and initiate skilled motor behaviors. Motor planning involves activity distributed widely across the cortex. How this activity dynamically comes together to guide mo...
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Chapter and Conference Paper
Erratum
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Erratum to: AGC1 Deficiency Causes Infantile Epilepsy, Abnormal Myelination, and Reduced N-Acetylaspartate
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Chapter
Human FcR Polymorphism and Disease
Fc receptors play a central role in maintaining the homeostatic balance in the immune system. Our knowledge of the structure and function of these receptors and their naturally occurring polymorphisms, includi...
