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Chapter
Alcohol Withdrawal Syndromes in the Human: Comparison with Animal Models
Alcohol withdrawal syndromes in humans lie on a continuum of increasing severity, from the acute hangover to delirium tremens. Early mild reactions consist primarily of hyperexcitability phenomena such as trem...
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Chapter
Comparative Aspects of Tolerance to, and Dependence on, Alcohol, Barbiturates and Opiates
Despite the known differences in mechanism of action of opiates and of the general depressants at molecular level, the withdrawal reactions after prolonged treatment with morphine, alcohol and barbiturates hav...
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Chapter
Biological Models of Alcohol Tolerance and Physical Dependence
Though tolerance to, and physical dependence on, ethanol have long been recognized, relatively little research has been devoted to the mechanisms by which these states are brought about. Comparatively, much mo...