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    Chapter

    Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis

    Circulating tumor cells offer an unprecedented window into the metastatic cascade, and to some extent can be considered as intermediates in the process of metastasis. They exhibit dynamic oscillations in epith...

    Risa Burr, Christine Gilles… in Circulating Tumor Cells in Breast Cancer M… (2020)

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    Chapter

    Matrix Metalloproteases and Epithelial-to-Mesenchymal Transition

    The epithelial to mesenchymal transition (EMT) is characterized by the loss of epithelial characteristics and the gain of mesenchymal attributes in epithelial cells. It has been associated with physiological a...

    Christine Gilles, Donald F. Newgreen, Hiroshi Sato… in Rise and Fall of Epithelial Phenotype (2005)