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Chapter and Conference Paper
Can ICA Help Classify Skin Cancer and Benign Lesions?
Various neural network models for the identification and classification of different skin lesions from ALA-induced fluorescence images are presented. After different image preprocessing steps, eigenimages and ...
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Chapter and Conference Paper
Einfluß von MIA auf die Lebermetastasierung von A-mel 3 Melanomzellen
MIA (melanoma inhibitory activity), ein 11 kD Protein, wird von malignen Melanomen (MM) sezerniert. Bisher konnte eine relevante MIA Expression in malignen Tumoren und differenzierten Chondrozyten gezeigt werd...
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Chapter and Conference Paper
ICG vermittelte, lokale photochemische Therapie von Hautmetastasen — Erste Erfahrungen einer palliativen Behandlung
The results of ICG-mediated photochemotherapy for superficial cutaneous metastases and a solid subcutaneous metastasis after i.v. application of ICG (2×2 mg/kg b.w.) with either surface or interstitial irradia...
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Chapter and Conference Paper
Photodynamic Therapy of Skin Cancers: A New Therapeutic Alternative?
A photodynamic reaction is the excitation of a photosensitizer, mainly porphyrin derivatives, by visible light emitted by lamps or lasers in the presence of oxygen resulting in the generation of reactive oxyge...
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Chapter and Conference Paper
Benzoporphyrinderivataufnahme in Kultivierten Myofibroblasten
Ein wesentliches Problem der perkutanen transluminalen Koronarangioplastie (PTCA) ist die hohe Rezidivstenoserate von 20–40% innerhalb der ersten sechs Monate (1). Die Proliferation von Zellen der arteriellen ...
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Chapter and Conference Paper
Fluoreszenzverteilung in Genitaldysplasien nach ALA-Applikation
Vor der klinischen Anwendung der photodynamischen Lasertherapie ist die Verteilung der durch topisch applizierte delta-Aminolävulinsäure (ALA) hervorgerufenen Fluoreszenz von Interesse. Wir haben bei 53 Patien...
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Chapter and Conference Paper
Evaluation der Durchblutung von Tumoren vor und nach photodynamischer Therapie mittels Natrium-Fluoreszein-Fluxmetrie
Die photodynamische Therapie (PDT) führt über primär zytotoxische und sekundär vaskuläre Mechanismen zur Tumorischämie und zur selektiven Nekrose des neo-plastischen Gewebes. Um die Auswirkung der PDT auf die ...
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Chapter and Conference Paper
Current Evidence on a Pathophysiological Function of Leukocyte/Endothelial Interactions in Cerebral Ischemia
Accumulation of leukocytes, particularly of polymorphonuclear neutrophils (PMNLs), is considered as an important response in tissue injury or infection. Recent investigations in a variety of organs, such as bo...
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Chapter and Conference Paper
Leukocyte/Endothelial Interactions and Blood-Brain Barrier Permeability in Rats During Cerebral Superfusion with LTB4
The experimental study analyses the vasomotor response (change of diameter of pial arterioles and venules), and blood-brain barrier function of the pia-arachnoidea at the rat brain surface before, during and a...
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Chapter and Conference Paper
White Blood Cell Behavior in the Cerebral Microcirculation
The role of white blood cells in acute cerebral disorders such as ischemia, stroke, or inflammation is not understood. Activated neutrophils might be involved, for example, in damage to the cerebrovascular end...
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Chapter and Conference Paper
Effect of Stimulation of Leukocyte Chemotaxis by fMLP on White Blood Cell Behaviour in the Microcirculation of Rat Brain
The role of white blood cells in acute cerebral disorders such as ischemia or stroke is still unclear. Therefore, in the present study we investigated the effects of the leukotaxin n-formyl-methionyl-leucylphe...