31 Result(s)

Article

Double blinded, vehicle controlled, crossover study on the efficacy of a topical endocannabinoid membrane transporter inhibitor in atopic Beagles

The endocannabinoid system is important for skin homeostasis and alterations are linked to inflammatory diseases like atopic dermatitis (AD). Importantly, activation of cannabinoid receptor CB2 decreases pruri...

Rosanna Marsella, K. Ahrens, R. Sanford, A. Trujillo… in Archives of Dermatological Research (2019)

Article

Determination of the antibacterial efficacy of a new porphyrin-based photosensitizer against MRSA ex vivo

Following extensive in vitro screening of new photosensitizers the purpose of the present study was to examine penetration as well as antibacterial efficacy of a lead photosensitizer against MRSA using an ex vivo

T. Maisch, C. Bosl, R. M. Szeimies, B. Love… in Photochemical & Photobiological Sciences (2007)

Article

Antibakterielle photodynamische Therapie

Grundlage der photodynamischen Inaktivierung von Bakterien ist die Generierung von reaktiven Sauerstoffspezies durch einen zellulär lokalisierten Photosensibilisator in Anwesenheit von Sauerstoff, der durch Li...

Dr. T. Maisch, R.-M. Szeimies, N. Lehn, C. Abels in Der Hautarzt (2005)

Article

Structure-activity relationships of three differently substituted 2,7,12,17-tetrakis-(β-methoxyethyl) porphycene derivatives in vitro

The subcellular localization, efficacy and photooxidative mechanism of three new photosensitizing porphycenes (HexoTMPn, PeloTMPn, CpoTMPn) for photodynamic therapy with different substituents at position 9 of...

Kathrin Scherer, C. Abels, W. Bäumler, G. Ackermann… in Archives of Dermatological Research (2004)

Article

Die kutane Mikrodialyse Anwendung in der Dermatologie

Bisher war die Bestimmung exogener oder endogener Substanzen in der Dermis z. B. im Rahmen pharmakokinetischer Untersuchungen nur mit Einschränkungen möglich. Die zur Verfügung stehenden Methoden wie die Entna...

A. Gottlob, C. Abels, M. Landthaler, R.-M. Szeimies in Der Hautarzt (2002)

Article

Bruchbandinduzierte makulöse Amyloidose

C. Abels, S. Karrer, M. Landthaler, R. M. Szeimies in Der Hautarzt (2001)

Article

Photochemotherapie kutaner Aids-assoziierter Kaposi-Sarkome mit Indocyaningrün und Laserlicht

R.-M. Szeimies, T. Lorenzen, S. Karrer, C. Abels, A. Plettenberg in Der Hautarzt (2001)

Chapter and Conference Paper

Can ICA Help Classify Skin Cancer and Benign Lesions?

Various neural network models for the identification and classification of different skin lesions from ALA-induced fluorescence images are presented. After different image preprocessing steps, eigenimages and ...

Ch. Mies, Ch. Bauer, G. Ackermann, W. Bäumler… in Bio-Inspired Applications of Connectionism (2001)

Article

Fluoreszenzgestützte Biopsie von Basalzellkarzinomen

G. Ackermann, C. Abels, S. Karrer, W. Bäumler, M. Landthaler… in Der Hautarzt (2000)

Article

Leukocyte-Endothelium-Interaction in Pial Vessels Following Global, Cerebral Ischaemia

¶ Background. Investigations have shown an increase of leukocyte-endothelium-interaction in a variety of organs following an ischaemic insult. To elucidate the role of leukocyte-endothelium-interaction following ...

C. Abels, F. Röhrich, S. Corvin, R. Meyermann, A. Baethmann… in Acta Neurochirurgica (2000)

Article

Photodynamic Inactivation of Staphylococci with 5-Aminolaevulinic Acid or Photofrin

Widespread use of antibiotics for bacterial infections is a reason for antibiotic resistance. Therefore, alternatives like photodynamic therapy (PDT) are studied for bacterial eradication.

S. Karrer, R.-M. Szeimies, S. Ernst, C. Abels, W. Bäumler… in Lasers in Medical Science (1999)

Chapter and Conference Paper

Einfluß von MIA auf die Lebermetastasierung von A-mel 3 Melanomzellen

MIA (melanoma inhibitory activity), ein 11 kD Protein, wird von malignen Melanomen (MM) sezerniert. Bisher konnte eine relevante MIA Expression in malignen Tumoren und differenzierten Chondrozyten gezeigt werd...

M. Guba, A.-K. Bosserhoff, M. Steinbauer… in Chirurgisches Forum ’99 für experimentelle… (1999)

Article

New Laser Literature

G J Tearney, M E Brezinski, F Southern, B E Bouma, S A Boppart… in Lasers in Medical Science (1998)

Article

Indocyanine green and laser light for the treatment of AIDS-associated cutaneous Kaposi's sarcoma

Indocyanine green (ICG) is clinically approved for the determination of liver function, cardiac output and plasma volume. In this pilot study, ICG was used as photosensitizer in combination with a diode laser ...

C Abels, S Karrer, W Bäumler, AE Goetz, M Landthaler… in British Journal of Cancer (1998)

Chapter and Conference Paper

ICG vermittelte, lokale photochemische Therapie von Hautmetastasen — Erste Erfahrungen einer palliativen Behandlung

The results of ICG-mediated photochemotherapy for superficial cutaneous metastases and a solid subcutaneous metastasis after i.v. application of ICG (2×2 mg/kg b.w.) with either surface or interstitial irradia...

W. E. Thasler, C. Abels, S. Karrer… in Vielfalt und Einheit der Chirurgie Humanit… (1998)

Article

Dosedependent photodynamic effects of 9-acetoxy-2,7,12,17-tetrakis(\-methoxyethyl)-porphycene in vitro

Porphycenes are chemically pure photosensitizers for topical and systemic photodynamic therapy (PDT). Fast cellular uptake of 9-acetoxy-2,7,12,17-tetrakis-(sB-methoxyethyl)porphycene (ATMPn) has been shown pre...

S. Karrer, R. M. Szeimies, A. Ebert, S. Fickweiler, C. Abels… in Lasers in Medical Science (1997)