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Chapter
Comparison of a New Brain Tissue Oxygenation Probe with the Established Standard
Introduction: Continuous bedside brain tissue oxygenation (pbrO2) monitoring using the Licox system is an established method for detecting secondary ischemia in comatose patients with acute brain i...
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Chapter
Drift of the Bowman Hemedex® Cerebral Blood Flow Monitor Between Calibration Cycles
Introduction: Since its introduction into clinical practice, the Bowman Hemedex® regional cerebral blood flow (CBF) monitor has provided a valuable tool for the bedside assessment of CBF in neuroin...
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Article
Continuous Selective Intraarterial Infusion of Nimodipine for Therapy of Refractory Cerebral Vasospasm
For endovascular treatment of vasospasm after aneurysmal subarachnoid hemorrhage (aSAH), an intraarterial treatment course with the calcium channel antagonist nimodipine infused for 30 min is proposed. As some...
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Article
Relationship of stroke volume variation, pulse pressure variation and global end-diastolic volume in patients undergoing brain surgery
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Article
Drift analysis of a novel device for measurement of regional cerebral blood flow
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Article
Comparison of a new brain tissue oxygenation measuring probe with the established standard
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Article
Global end-diastolic volume and global end-diastolic volume index are age dependent in awake, spontaneous-breathing patients after elective craniotomy
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Chapter and Conference Paper
Qualitative aspects of cranial CT perfusion scanning in a mixed neurosurgical patient collective
Background In patients with ischemic stroke, computer tomography (CT) perfusion imaging provides rapid information on the penumbra adjacent to the infarct core. For neurosurgical patients...
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Article
The repeatability of transpulmonary thermodilution measurements
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Chapter and Conference Paper
The Safety of the Open Lung Approach in Neurosurgical Patients
A recent randomized controlled trial in patients with ARDS showed the beneficial effect of mechanical ventilation according to the so called Open Lung Approach, consisting of low tidal volumes and elevated PEEP s...
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Article
Comparison of two thermodilution devices for postoperative care in patients with aneurysmal subarachnoid hemorrhage
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Article
Open lung strategies in patients with intracranial lesions and acute lung injury
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Article
Leukocyte-Endothelium-Interaction in Pial Vessels Following Global, Cerebral Ischaemia
¶ Background. Investigations have shown an increase of leukocyte-endothelium-interaction in a variety of organs following an ischaemic insult. To elucidate the role of leukocyte-endothelium-interaction following ...
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Article
The CAMINO Intracranial Pressure Device in Clinical Practice: Reliability, Handling Characteristics and Complications
Intracranial pressure monitoring has a key role in the management of patients develo** increased intracranial pressure (ICP). We adopted the Camino fiberoptic system for intracranial pressure measurement in...
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Chapter
Schädel-Hirn-Trauma
Das Schädel-Hirn-Trauma (SHT) ist in den industrialisierten Ländern die häufigste Todesursache von Jugendlichen und Erwachsenen bis zum 40. Lebensjahr. In Deutschland erleiden jährlich etwa 30000 Menschen ein ...
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Article
Cerebral lactate production in relation to intracranial pressure, cranial computed tomography findings, and outcome in patients with severe head injury
Severe head injury is frequently associated with focal or global disturbances of cerebral blood flow and metabolism. Routine monitoring of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in t...
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Article
A novel, remote-controlled suspension device for brain tissue PO2 measurements with multiwire surface electrodes
A new device was developed for rapid assessment of PO2 values in viable tissue, such as the brain, using a multiwire surface electrode. The instrument utilizes a phonograph-like construction with weightless suspe...
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Chapter and Conference Paper
Growth Kinetics of a Primary Brain Tissue Necrosis from a Focal Lesion
Secondary brain damage, such as brain edema or impairment of the cerebral microcirculation may evolve from tissue necrosis of the brain induced by trauma or ischemia. This laboratory has provided novel informa...
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Chapter and Conference Paper
Secondary Growth of a Primary Brain Tissue Necrosis from a Focal Lesion
Traumatic brain injury is associated with the development of secondary brain damage, such as brain edema, intracranial hypertension, and cerebral ischemia [1]. A novel aspect is that a primary necrosis of brai...
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Chapter and Conference Paper
7.2% NaCl/10% Dextran 60 versus 20% Mannitol for Treatment of Intracranial Hypertension
Severe head injury is frequently associated with extracranial injuries causing hemorrhagic hypotension. Volume replacement with isotonic fluids not only is therapeutically of limited efficacy but may aggravate...
