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  1. No Access

    Article

    The Influence of the Synthetic Organoselenium Preparation 974zh on the Immunogenic Activity of Yersinia pestis EV Vaccine Strain NIIEG

    In the present study, a stimulating effect of a new synthetic organoselenium compound 2,6-dipyridinium-9-selenabicyclo[3.3.1]nonandibromide (974zh) on the immunogenic activity of the vaccine strain Yersinia pesti...

    V. I. Dubrovina, O. V. Yur’eva… in Bulletin of Experimental Biology and Medic… (2023)

  2. No Access

    Article

    Immunotropic Properties of an Experimental Synthetic Selenium-Organic Compound

    We studied immunotropic properties of synthetic selenium-organic preparation 2,6-dipyridinium-9-selenabicyclo[3.3.1]nonyl dibromide (974zh). The experimental preparation reduced the cAMP/cGMP ratio, which indi...

    O. V. Yur’eva, V. I. Dubrovina… in Bulletin of Experimental Biology and Medic… (2020)

  3. No Access

    Article

    Effect of Synthetic Organoselenium Drug on the Degree of Pathological Changes in the Organs of White Mice Immunized with Tularemia and Brucellosis Vaccines

    We studied the effect of the organoselenium compound 2,6-dipyridinium-9-selenium-bicyclo[ 3,3,1]nonan dibromide (974zh) on the severity of pathological changes in the organs of experimental animals immunized w...

    O. V. Yurieva, V. I. Dubrovina… in Bulletin of Experimental Biology and Medic… (2019)

  4. No Access

    Article

    Immunogenesis in White Mice Infected with Yersinia pestis with Different Plasmid Composition

    Morphological changes in the immunocompetent organs of white mice with experimental plague infection manifested in activation of the immune response of different degree and pathological process of different se...

    S. V. Balakhonov, S. A. Vityazeva… in Bulletin of Experimental Biology and Medic… (2017)

  5. No Access

    Article

    Effect of Corticotropin-Like Intermediate Lobe Peptide on Presynaptic and Postsynaptic Glutamate Receptors and Postsynaptic GABA Receptors in Rat Brain

    We studied the effect of corticotropin-like intermediate lobe peptide (CLIP) on presynaptic NMDA receptors and postsynaptic GABA, NMDA, and AMPA receptors in rat brain. CLIP inhibited presynaptic and postsynap...

    V. V. Grigoriev, L. N. Petrova… in Bulletin of Experimental Biology and Medic… (2009)

  6. No Access

    Article

    Effect of muramyl dipeptides on postsynaptic GABA, NMDA, and AMPA receptors and presynaptic NMDA receptors in rat brain

    We studied the effect of muramyl dipeptides on postsynaptic GABA, NMDA, and AMPA receptors and presynaptic NMDA receptors. L,D-Dipeptide more potently than L,L-dipeptide inhibited postsynaptic NMDA receptors, ...

    V. V. Grigoriev, L. N. Petrova… in Bulletin of Experimental Biology and Medic… (2008)

  7. No Access

    Article

    Effects of delta sleep-inducing peptide on pre-and postsynaptic glutamate and postsynaptic GABA receptors in neurons of the cortex, hippocampus, and cerebellum in rats

    We studied the effect of delta sleep-inducing peptide on GABA receptors of hippocampal and cerebellar neurons in rats. It was shown that delta sleep-inducing peptide considerably and dose-dependently potentiat...

    V. V. Grigor’ev, T. A. Ivanova… in Bulletin of Experimental Biology and Medic… (2006)

  8. No Access

    Article

    Effects of 17β-estradiol and its isomer 17α-estradiol on learning in rats with chronic cholinergic deficiency in the brain

    It was shown for the first time that estrogens 17β- and 17α-estradiols compensate impaired cognitive functions in rats with partial chronic deprivation of cholinergic functions in the central nervous system in...

    N. N. Lermontova, V. K. P'chev… in Bulletin of Experimental Biology and Medic… (2000)

  9. No Access

    Article

    Correlations between mitotic indices of bone marrow cells in dogs

    The mitotic indices of erythroblasts, basophilic and polychromatophilic normoblasts, myeloblasts, promyelocytes, and myelocytes were shown to decrease depending on the degree of differentiation of the cells in...

    T. A. Ivanova, A. A. Gordeeva… in Bulletin of Experimental Biology and Medic… (1979)