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Open AccessPortable impedance-sensing device for microorganism characterization in the field
A variety of biosensors have been proposed to quickly detect and measure the properties of individual microorganisms among heterogeneous populations, but challenges related to cost, portability, stability, sen...
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Electrochemiluminescent immunosensor for detection of carcinoembryonic antigen using luminol-coated silver nanoparticles
Recently, electrochemiluminescent (ECL) immunosensors have received much attention in the field of biomarker detection. Here, a highly enhanced ECL immunosensing platform was designed for ultrasensitive detect...
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Open AccessVery Selective Detection of Low Physiopathological Glucose Levels by Spontaneous Raman Spectroscopy with Univariate Data Analysis
After decades of research on non-invasive glucose monitoring, invasive devices based on finger blood sampling are still the predominant reference for diabetic patients for accurately measuring blood glucose le...
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Open AccessThe Michelangelo step: removing scallo** and tapering effects in high aspect ratio through silicon vias
We present here, for the first time, a fabrication technique that allows manufacturing scallop free,
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Biosensors for Biomolecular Computing: a Review and Future Perspectives
Biomolecular computing is the field of engineering where computation, storage, communication, and coding are obtained by exploiting interactions between biomolecules, especially DNA, RNA, and enzymes. They are...
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Milk Allergen Detection: Sensitive Label-Free Voltammetric Immunosensor Based on Electropolymerization
We present in this work, first time in literature, a voltammetric label-free biosensor for detection of alpha lactalbumin (α-LB) in meal samples. Food allergy concern necessitates strict regulations in food la...
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Open AccessElectrochemical detection of different p53 conformations by using nanostructured surfaces
Protein electrochemistry represents a powerful technique for investigating the function and structure of proteins. Currently available biochemical assays provide limited information related to the conformation...
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Article
Open AccessLabel-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells
Nanoscale extracellular vesicles (EVs) including exosomes (50–150 nm membrane particles) have emerged as promising cancer biomarkers due to the carried genetic information about the parental cells. However the...
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Highly Sensitive Enzymatic MWCNTs-Based Biosensors for Detection of Abiraterone in Human Serum
A highly sensitive enzymatic biosensor is successfully experimented for detection of abiraterone in human serum with significance in personalized medicine and point-of-care chemotherapy of patients with metast...
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Open AccessGoogle Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators
Google Glass is a recently designed wearable device capable of displaying information in a smartphone-like hands-free format by wireless communication. The Glass also provides convenient control over remote de...
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Open AccessFast synthesis of platinum nanopetals and nanospheres for highly-sensitive non-enzymatic detection of glucose and selective sensing of ions
Novel methods to obtain Pt nanostructured electrodes have raised particular interest due to their high performance in electrochemistry. Several nanostructuration methods proposed in the literature use costly a...
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Electrochemical nanostructured biosensors: carbon nanotubes versus conductive and semi-conductive nanoparticles
The aim of this work was to demonstrate that various types of nanostructures provide different gains in terms of sensitivity or detection limit albeit providing the same gain in terms of increased area. Commer...
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Empowering Low-Cost CMOS Cameras by Image Processing to Reach Comparable Results with Costly CCDs
Despite the huge research effort to improve the performance of the complementary metal oxide semiconductor (CMOS) image sensors, charge-coupled devices (CCDs) still dominate the cell biology-related convention...
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Comparative Performance of Different Nanostructured Electrochemical Sensors on Insulin Detection
New advancements in the management of type I diabetic patients (T1DM) call for a new generation of monitoring systems based upon an array of metabolic biosensors including sensors for insulin detection. Blood ...
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Article
Multiwalled Carbon Nanotubes for Amperometric Array-Based Biosensors
For diagnostic and therapeutic purposes an accurate determination of multiple metabolites is often required. Amperometric devices are attractive tools to quantify biological compounds due to the direct convers...
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Article
Simulated Biological Cells for Receptor Counting in Fluorescence Imaging
Digital image processing and epifluorescence microscopy provide one of the main and basic tools for living biological cell analysis and studying. Develo**, testing, and comparing those image processing metho...
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Biochips for Regenerative Medicine: Real-time Stem Cell Continuous Monitoring as Inferred by High-Throughput Gene Analysis
Regenerative medicine is a novel clinical branch aiming at the cure of diseases by replacement of damaged tissues. The crucial use of stem cells makes this area rich of challenges, given the poorly understood ...
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New Insight on Bio-sensing by Nano-fabricated Memristors
We report here on a new insight for bio-sensing based on the memristive effect of functionalized Schottky-barrier memristive silicon nanowire in dry environment. The device concept is discussed. Electrical mea...
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Article
High order DNA structure as inferred by optical fluorimetry and scanning calorimetry
New quantitative insights on the native high order chromatin-DNA structure existing within interphase nuclei are obtained by monitoring the effects of two common well-characterized fixatives, glutaraldehyde an...