4 Result(s)
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Article
Rafiqul Hussain
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessSingle-cell analyses reveal transient retinal progenitor cells in the ciliary margin of develo** human retina
The emergence of retinal progenitor cells and differentiation to various retinal cell types represent fundamental processes during retinal development. Herein, we provide a comprehensive single cell characteri...
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Article
Open AccessSingle-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission
Immune-mediated inflammatory diseases (IMIDs) are typically characterised by relapsing and remitting flares of inflammation. However, the unpredictability of disease flares impedes their study. Addressing this...
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Article
Open AccessDelayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2
The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon (IFN) responses are critical to o...
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Article
Blood and immune development in human fetal bone marrow and Down syndrome
Haematopoiesis in the bone marrow (BM) maintains blood and immune cell production throughout postnatal life. Haematopoiesis first emerges in human BM at 11–12 weeks after conception1,2, yet almost nothing is know...
