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  1. Article

    Open Access

    Appropriateness of the EQ-5D-5L in capturing health-related quality of life in individuals with transfusion-dependent β-thalassemia: a mixed methods study

    Individuals with transfusion-dependent β-thalassemia (TDT) experience symptoms and functional impacts that reduce their health-related quality of life. However, EQ-5D-derived health utility index scores in TDT...

    Adriana Boateng-Kuffour, Hanna Skrobanski in Health and Quality of Life Outcomes (2024)

  2. Article

    Open Access

    Health-Related Quality-of-Life Impacts Associated with Transfusion-Dependent β-Thalassemia in the USA and UK: A Qualitative Assessment

    Individuals living with transfusion-dependent β-thalassemia (TDT) experience reduced health-related quality of life due to fatigue and chronic pain, which cause disruptions to daily life. Currently, limited qu...

    Jennifer Drahos, Adriana Boateng-Kuffour in The Patient - Patient-Centered Outcomes Re… (2024)

  3. Article

    Open Access

    Correction to: Economic and Clinical Burden of Managing Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in the United States

    Chuka Udeze, Kristin A. Evans, Yoojung Yang, Timothy Lillehaugen in Advances in Therapy (2023)

  4. Article

    Open Access

    Economic and Clinical Burden of Managing Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in the United States

    The aim of this study was to describe the clinical complications, treatment use, healthcare resource utilization (HCRU), and costs among patients with sickle cell disease (SCD) with recurrent vaso-occlusive cr...

    Chuka Udeze, Kristin A. Evans, Yoojung Yang, Timothy Lillehaugen in Advances in Therapy (2023)

  5. No Access

    Article

    Levels, source apportionment, and risk assessment of polycyclic aromatic hydrocarbons in vegetable bases of northwest China

    Dietary consumption of contaminated vegetables is the main route of human exposure to polycyclic aromatic hydrocarbons (PAHs). However, there is a lack of research on PAHs in vegetables from northwest China. I...

    Nuerla Ailijiang, ** Cui, Anwar Mamat in Environmental Geochemistry and Health (2023)

  6. No Access

    Article

    Pollution levels, sources and risk assessment of polycyclic aromatic hydrocarbons in farmland soil and crops near Urumqi Industrial Park, **njiang, China

    This study investigated the concentration, source, and risk assessment of polycyclic aromatic hydrocarbons (PAHs) in farmland soil and crops around the Urumqi Industrial Park in **njiang, China. The total conc...

    ** Cui, Nuerla Ailijiang in Stochastic Environmental Research and Risk… (2023)

  7. Article

    Open Access

    Levels, sources, and risk assessment of PAHs residues in soil and plants in urban parks of Northwest China

    Polycyclic aromatic hydrocarbons (PAHs) will be ingested by people through different ways to threaten their health during play, so the environmental quality of the park directly affects the health of tourists ...

    Nuerla Ailijiang, Naifu Zhong, **aolong Zhou, Anwar Mamat in Scientific Reports (2022)

  8. Article

    Open Access

    Clinical, humanistic, and economic burden of severe haemophilia B in adults receiving factor IX prophylaxis: findings from the CHESS II real-world burden of illness study in Europe

    Real-world studies of the burden of severe haemophilia B in the context of recent therapeutic advances such as extended half-life (EHL) factor IX (FIX) products are limited. We analysed data from the recent CH...

    Tom Burke, Sohaib Asghar, Jamie O’Hara in Orphanet Journal of Rare Diseases (2021)

  9. Article

    Open Access

    Clinical, humanistic, and economic burden of severe hemophilia B in the United States: Results from the CHESS US and CHESS US+ population surveys

    Hemophilia B is a rare congenital bleeding disorder that has a significant negative impact on patients’ functionality and health-related quality of life. The standard of care for severe hemophilia B in the Uni...

    Tom Burke, Sohaib Asghar, Jamie O’Hara in Orphanet Journal of Rare Diseases (2021)

  10. Article

    Open Access

    The scientific elucidation of daodi medicinal materials

    Daodi medicinal materials (DMMs), with unique characteristics and specific ecological growing environments, are recognized as high-quality medicinal products of Chinese medicinal materials (CMMs). The quality eva...

    **ndan Liu, Ying Zhang, Menghua Wu, Zhiguo Ma, Zihan Huang, Fang Tian in Chinese Medicine (2020)

  11. Article

    Open Access

    Cost-Effectiveness Analysis of Recombinant Factor VIII Fc-Fusion Protein (rFVIIIFc) for the Treatment of Severe Hemophilia A in Italy Incorporating Real-World Dosing and Joint Health Data

    Patients with severe hemophilia A (SHA) in Italy are routinely treated with standard half-life recombinant factor VIII (rFVIII) products. rFVIII Fc-fusion protein (rFVIIIFc) is an extended half-life rFVIII pro...

    Ash Bullement, Samuel Thomas McMordie, Anthony James Hatswell in PharmacoEconomics - Open (2020)

  12. Article

    Open Access

    Chromatographic fingerprints analysis and determination of seven components in Danmu preparations by HPLC–DAD/QTOF-MS

    Danmu preparations (Danmu Capsule and Danmu Syrup), which are made from Nauclea officinalis stem extracts, have good clinical efficacy in acute tonsillitis, acute pharyngitis and upper respiratory tract infection...

    Nanxin Li, **ju Zhang, Ying Zhang, Zhiguo Ma, **hong Liao, Hui Cao in Chinese Medicine (2020)

  13. No Access

    Article

    Cost Effectiveness of Midostaurin in the Treatment of Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia in the United States

    The aim of this study was to assess the cost effectiveness of midostaurin + cytarabine + daunorubicin (midostaurin arm) versus placebo + cytarabine + daunorubicin (placebo arm) in the treatment of adult patien...

    Eytan Stein, Jipan **e, Emilie Duchesneau, Subrata Bhattacharyya in PharmacoEconomics (2019)

  14. No Access

    Article

    Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

    Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan in Nature (2019)

  15. Article

    Open Access

    Clinical and Economic Outcomes in Elderly Advanced Renal Cell Carcinoma Patients Starting Pazopanib or Sunitinib Treatment: A Retrospective Medicare Claims Analysis

    Studies indicate similar survival and toxicity between pazopanib and sunitinib, but few have examined real-world outcomes among elderly patients with advanced renal cell carcinoma (RCC). The purpose of this re...

    Nicholas J. Vogelzang, Sumanta K. Pal, Sameer R. Ghate in Advances in Therapy (2017)

  16. No Access

    Article

    Real-World Analysis of Medical Costs and Healthcare Resource Utilization in Elderly Women with HR+/HER2− Metastatic Breast Cancer Receiving Everolimus-Based Therapy or Chemotherapy

    The objective of this study was to analyze medical costs and healthcare resource utilization (HRU) associated with everolimus-based therapy or chemotherapy among elderly women with hormone-receptor-positive, h...

    Yanni Hao, Nanxin Li, Anna P. Fang, Valerie Koo, Miranda Peeples in Advances in Therapy (2016)

  17. Article

    Open Access

    Clinical outcomes among HR+/HER2− metastatic breast cancer patients with multiple metastatic sites: a chart review study in the US

    Hormone receptor-positive, human epidermal growth factor receptor-2-negative (HR+/HER2−) is the most common type of metastatic breast cancer (mBC). While mBC patients generally have poor prognosis with limited...

    Jipan **e, Yanni Hao, Nanxin Li, Peggy L. Lin in Experimental Hematology & Oncology (2015)

  18. No Access

    Article

    TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts

    Neuroblastoma (NB) is one of the most common and deadly pediatric solid tumors. NB is characterized by clinical heterogeneity, from spontaneous regression to relentless progression despite intensive multimoda...

    Jamie L. Croucher, Radhika Iyer, Nanxin Li in Cancer Chemotherapy and Pharmacology (2015)

  19. No Access

    Article

    Treatment, Monitoring, and Economic Outcomes of Venous Thromboembolism Among Hospitalized Patients in China

    The prevalence of venous thromboembolism (VTE) has been increasing in China. However, the treatment pattern and economic burden of these patients have not been well-understood.

    Eric Q. Wu, Jipan **e, Chun Wu, Ella **aoyan Du, Nanxin Li in PharmacoEconomics (2014)

  20. Article

    Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

    Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan in Nature (2012)

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