40 Result(s)

Article

Correction to: Discontinuation and Switchback After Non-Medical Switching from Originator Tumor Necrosis Factor Alpha (TNF) Inhibitors to Biosimilars: A Meta-Analysis of Real-World Studies from 2012 to 2018

Yifei Liu, Martha Skup, Min Yang, Cynthia Z. Qi, Eric Q. Wu in Advances in Therapy (2022)

Article

Discontinuation and Switchback After Non-Medical Switching from Originator Tumor Necrosis Factor Alpha (TNF) Inhibitors to Biosimilars: A Meta-Analysis of Real-World Studies from 2012 to 2018

To examine the prevalence rates of biosimilar discontinuation and switchback to the originator tumor necrosis factor alpha (TNF) inhibitors following non-medical switch (NMS) in patients.

Yifei Liu, Martha Skup, Min Yang, Cynthia Z. Qi, Eric Q. Wu in Advances in Therapy (2022)

Article

The Economic Burden of Eosinophilic Gastritis and Eosinophilic Enteritis in the United States

Eosinophilic gastritis and eosinophilic enteritis (EoG/EoN) are associated with a substantial clinical burden. However, limited information is available regarding the economic burden of EoG/EoN. This study was...

Michael Woolley, Erin E. Cook, Fan Mu, Keith A. Betts, Emma Billmyer… in Advances in Therapy (2022)

Article

Real-World Management of Hyperkalemia in the Emergency Department: An Electronic Medical Record Analysis

Hyperkalemia is often managed in the emergency department (ED) and it is important to understand how ED management and post-discharge outcomes vary by hyperkalemia severity. This study was conducted to charact...

Jill Davis, Rubeen Israni, Keith A. Betts, Fan Mu, Erin E. Cook… in Advances in Therapy (2022)

Article

Prevalence of Metabolic Acidosis Among Patients with Chronic Kidney Disease and Hyperkalemia

Although hyperkalemia and metabolic acidosis often co-occur in patients with chronic kidney disease (CKD), the prevalence of metabolic acidosis among patients with CKD and hyperkalemia is understudied. Therefo...

Erin E. Cook, Jill Davis, Rubeen Israni, Fan Mu, Keith A. Betts… in Advances in Therapy (2021)

Article

Real-World Treatment Profiles, Clinical Outcomes, and Healthcare Resource Utilization of Patients with Migraine Prescribed Erenumab: A Multicenter Chart-Review Study of US Headache Centers

Erenumab, a first-in-class monoclonal antibody targeting the calcitonin gene-related peptide pathway, was approved by the US Food and Drug Administration in 2018 for the prevention of migraine in adults. There...

Elizabeth Faust, Irina Pivneva, Karen Yang, Keith A. Betts… in Neurology and Therapy (2021)

Article

Response to: Alfred Sandrock, Wildon Farwell. Letter to the Editor, Comparisons Between Separately Conducted Clinical Trials: Letter to the Editor Regarding Dabbous O, Maru B, Jansen JP, Lorenzi M, Cloutier M, Guérin A, et al. Adv Ther (2019) 36(5):1164-76. doi:10.1007/s12325-019-00923-8

Omar Dabbous, Benit Maru, Jeroen P. Jansen, Maria Lorenzi… in Advances in Therapy (2019)

Article

Assessing Patient Preferences for Treatment Decisions for New Direct Acting Antiviral (DAA) Therapies for Chronic Hepatitis C Virus Infections

The new direct acting antiviral (DAA) therapies are able to effectively treat chronic hepatitis C (CHC). This study elicited the preferences of CHC patients for treatment attributes of new DAAs.

Tania M. Welzel, Min Yang, Gautam Sajeev, Yaozhu J. Chen… in Advances in Therapy (2019)

Article

Economic Impact of Non-Medical Switching from Originator Biologics to Biosimilars: A Systematic Literature Review

A systematic literature review was conducted to review and summarize the economic impact of non-medical switching (NMS) from biologic originators to their biosimilars (i.e., switching a patient’s medication fo...

Yifei Liu, Min Yang, Vishvas Garg, Eric Q. Wu, Jessie Wang… in Advances in Therapy (2019)

Article

Survival, Motor Function, and Motor Milestones: Comparison of AVXS-101 Relative to Nusinersen for the Treatment of Infants with Spinal Muscular Atrophy Type 1

Infants with spinal muscular atrophy (SMA) type 1 typically face a decline in motor function and a severely shortened life expectancy. Clinical trials for SMA type 1 therapies, onasemnogene abeparvovec (AVXS-1...

Omar Dabbous, Benit Maru, Jeroen P. Jansen, Maria Lorenzi… in Advances in Therapy (2019)

Article

Clinical Trajectories, Healthcare Resource Use, and Costs of Diabetic Nephropathy Among Patients with Type 2 Diabetes: A Latent Class Analysis

Patients with type 2 diabetes mellitus (T2DM) are clinically heterogeneous in terms of disease severity, treatment, and comorbidities, potentially resulting in differential diabetic nephropathy (DN) progressio...

Ruixuan Jiang, Ernest Law, Zhou Zhou, Hongbo Yang, Eric Q. Wu… in Diabetes Therapy (2018)

Article

Healthcare Resource Use, Costs, and Disease Progression Associated with Diabetic Nephropathy in Adults with Type 2 Diabetes: A Retrospective Observational Study

Diabetic nephropathy (DN) is a progressive kidney disease resulting as a complication of diabetes mellitus. This study evaluated the disease progression and economic burden of DN among commercially insured pat...

Zhou Zhou, Paresh Chaudhari, Hongbo Yang, Anna P. Fang, **g Zhao… in Diabetes Therapy (2017)

Article

Readmission Risk in Chronic Obstructive Pulmonary Disease Patients: Comparative Study of Nebulized β₂-Agonists

Bronchodilators are used for managing the symptoms of chronic obstructive pulmonary disease (COPD) and minimizing the risk of hospitalization and readmission. Hospital readmission is predictive of morbidity an...

Vamsi Bollu, Annie Guérin, Geneviève Gauthier… in Drugs - Real World Outcomes (2017)

Article

Cost-Effectiveness Analysis of Isavuconazole vs. Voriconazole as First-Line Treatment for Invasive Aspergillosis

Invasive aspergillosis (IA) is associated with a significant clinical and economic burden. The phase III SECURE trial demonstrated non-inferiority in clinical efficacy between isavuconazole and voriconazole. N...

Rachel Harrington, Edward Lee, Hongbo Yang, ** Wei, Andrew Messali… in Advances in Therapy (2017)

Article

Network Meta-Analysis and Cost Per Responder of Tumor Necrosis Factor-α and Interleukin Inhibitors in the Treatment of Active Ankylosing Spondylitis

Biologic therapies have improved the clinical management of ankylosing spondylitis (AS). Few head-to-head studies have directly compared the efficacy of these agents. This study was conducted to indirectly com...

Keith A. Betts, Jenny Griffith, Yan Song, Manish Mittal… in Rheumatology and Therapy (2016)

Article

Delay in initiation of adjuvant trastuzumab therapy leads to decreased overall survival and relapse-free survival in patients with HER2-positive non-metastatic breast cancer

Trastuzumab reduces the risk of relapse in women with HER2-positive non-metastatic breast cancer, but little information exists on the timing of trastuzumab initiation. The study investigated the impact of de...

Christopher M. Gallagher, Kenneth More… in Breast Cancer Research and Treatment (2016)