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Article
Open AccessSmaller stencil preconditioners for linear systems in RBF-FD discretizations
Radial basis function finite difference (RBF-FD) discretization has recently emerged as an alternative to classical finite difference or finite element discretization of (systems) of partial differential equat...
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Article
Open AccessLocal Administrations of Iron Oxide Nanoparticles in the Prefrontal Cortex and Caudate Putamen of Rats Do Not Compromise Working Memory and Motor Activity
Iron oxide nanoparticles (IONPs) have come into focus for their use in medical applications although possible health risks for humans, especially in terms of brain functions, have not yet been fully clarified....
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Article
Sonographie des Halses – differenzialdiagnostische Aspekte
Die Sonographie stellt die bevorzugte Methode für die Primärdiagnose und die Akutversorgung bei Pathologien im Bereich der Halsweichteile dar. Technologische Fortschritte, insbesondere eine hohe Bildauflösung ...
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Article
Open AccessUltrasound in the diagnosis and differential diagnosis of enoral and plunging ranula: a detailed and comparative analysis
To develop sonographic criteria for ranula that to allow rapid and precise diagnosis, differentiation between enoral (ER) and plunging ranula (PR), and differential diagnosis from other competing pathologies i...
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Article
Open AccessValidity of tissue homogeneity in confocal laser endomicroscopy on the diagnosis of laryngeal and hypopharyngeal squamous cell carcinoma
Confocal laser endomicroscopy (CLE) allows imaging of the laryngeal mucosa in a thousand-fold magnification. This study analyzes differences in tissue homogeneity between healthy mucosa and squamous cell carci...
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Article
Open AccessGenome wide association study of frost tolerance in wheat
Winter wheat growing areas in the Northern hemisphere are regularly exposed to heavy frost. Due to the negative impact on yield, the identification of genetic factors controlling frost tolerance (FroT) and dev...
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Article
Open AccessSalvage-Laryngektomie nach primärer Radio- und Radiochemotherapie
Das rezidivierende und residuelle Larynxkarzinom nach organerhaltender Radio- bzw. Radiochemotherapie ist mit einer schlechten Prognose verbunden. Die Salvage-Operation stellt in diesen Fällen die wichtigste t...
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Article
Open AccessEffects of Local Administration of Iron Oxide Nanoparticles in the Prefrontal Cortex, Striatum, and Hippocampus of Rats
Iron oxide nanoparticles (IONPs) are used for diverse medical approaches, although the potential health risks, for example adverse effects on brain functions, are not fully clarified. Several in vitro studies ...
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Article
Open AccessOperationalizing the Benefit of Information Radiators from an Awareness Point of View
In this paper, we present a grounded theory research for the benefit information radiators provided using the concept of awareness. Information radiators are ubiquitous installations that disseminate informati...
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Article
ADEO: the European commercial passive de-orbit subsystem family enabling space debris mitigation
The ADEO subsystem is a scalable drag augmentation device that uses the residual Earth atmosphere present in Low Earth Orbit (LEO) to passively de-orbit of satellites between 1 and 2000 kg. For the de-orbit ma...
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Open AccessErratum zu: Mensch-Computer-Interaktion als zentrales Gebiet der Informatik – Bestandsaufnahme, Trends und Herausforderungen
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Article
Open AccessSalvage laryngectomy after primary radio- and radiochemotherapy
Recurrent and residual laryngeal cancer after organ-preserving radio- or radiochemotherapy is associated with a poor prognosis. Salvage surgery is the most important therapeutic option in these cases.
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Article
Open AccessPostoperative management of antithrombotic medication in microvascular head and neck reconstruction: a comparative analysis of unfractionated and low-molecular-weight heparin
Free flap reconstruction is a valuable technique to preserve function in oncological head and neck surgery. Postoperative graft thrombosis is a dreaded risk. This study aims to compare low-dose unfractionated ...
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Article
Open AccessLong-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis
Organoids are morphologically heterogeneous three-dimensional cell culture systems and serve as an ideal model for understanding the principles of collective cell behaviour in mammalian organs during developme...
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Article
Open AccessHuman extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
The development, homeostasis, and repair of intrahepatic and extrahepatic bile ducts are thought to involve distinct mechanisms including proliferation and maturation of cholangiocyte and progenitor cells. Thi...
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Article
Open AccessMensch-Computer-Interaktion als zentrales Gebiet der Informatik – Bestandsaufnahme, Trends und Herausforderungen
Mensch-Computer-Interaktion (MCI) beschäftigt sich mit Fragen rund um die benutzer- und kontextegerechte Gestaltung von IT-Systemen. Ohne MCI ist die vielbeschworene digitale Transformation nicht möglich, da S...
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Article
Open AccessAdvanced paternal age as a risk factor for neurodevelopmental disorders: a translational study
Advanced paternal age (APA) is a risk factor for several neurodevelopmental disorders, including autism and schizophrenia. The potential mechanisms conferring this risk are poorly understood. Here, we show tha...
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Article
Incidence and relative risk of renal replacement therapy in people with and without diabetes between 2002 and 2016 in a German region
Data on trends of end-stage renal disease among people with diabetes are lacking. We analysed the incidence of end-stage renal disease, defined as renal replacement therapy, among people with and without diabe...
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Article
Outcome and management of rare high-grade “salivary” adenocarcinoma: the important role of adjuvant (chemo)radiotherapy
To determine survival and management strategies for high-grade adenocarcinoma of salivary glands (ASG).
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Article
Open AccessUltra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens
In three-dimensional light microscopy, the heterogeneity of the optical density in a specimen ultimately limits the achievable penetration depth and hence the three-dimensional resolution. The most direct appr...