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  1. Article

    Open Access

    Oral mucosa - an examination map for confocal laser endomicroscopy within the oral cavity: an experimental clinical study

    Confocal laser endomicroscopy (CLE) is an optical method that enables microscopic visualization of oral mucosa. Previous studies have shown that it is possible to differentiate between physiological and malign...

    Nicolai Oetter, Jonas Pröll, Matti Sievert in Clinical Oral Investigations (2024)

  2. No Access

    Article

    Diagnosis of malignancy in oropharyngeal confocal laser endomicroscopy using GPT 4.0 with vision

    Confocal Laser Endomicroscopy (CLE) is an imaging tool, that has demonstrated potential for intraoperative, real-time, non-invasive, microscopical assessment of surgical margins of oropharyngeal squamous cell ...

    Matti Sievert, Marc Aubreville in European Archives of Oto-Rhino-Laryngology (2024)

  3. No Access

    Chapter and Conference Paper

    Few Shot Learning for the Classification of Confocal Laser Endomicroscopy Images of Head and Neck Tumors

    The surgical removal of head and neck tumors requires safe margins, which are usually confirmed intraoperatively by means of frozen sections. This method is, in itself, an oversampling procedure, which has a r...

    Marc Aubreville, Zhaoya Pan, Matti Sievert in Bildverarbeitung für die Medizin 2024 (2024)

  4. Article

    Open Access

    A comparison between p16-positive head and neck cancer of unknown primary (HPV-HNCUP) and oropharyngeal squamous cell carcinoma (HPV-OPSCC): are they the same disease?

    The following study aimed to answer the question if HPV-HNCUP and HPV-OPSCC are the same disease. Propensity score matching (PSM) was used to compare the oncological outcomes of both groups, in particular the ...

    Matthias Balk, Robin Rupp, Matti Sievert in European Archives of Oto-Rhino-Laryngology (2023)

  5. Article

    Open Access

    Ultrasound in the diagnosis and differential diagnosis of enoral and plunging ranula: a detailed and comparative analysis

    To develop sonographic criteria for ranula that to allow rapid and precise diagnosis, differentiation between enoral (ER) and plunging ranula (PR), and differential diagnosis from other competing pathologies i...

    Michael Koch, Konstantinos Mantsopoulos, Victoria Leibl in Journal of Ultrasound (2023)

  6. Article

    Open Access

    Risk of magnetic resonance imaging-induced magnet dislocation for different types of cochlear implants: a single-center retrospective study

    When performing magnetic resonance imaging (MRI) in patients with a cochlear implant (CI), complication rates vary widely in the literature. The primary objective of this retrospective study was to determine t...

    Robin Rupp, Matthias Balk, Matti Sievert in Journal of Otolaryngology - Head & Neck Su… (2023)

  7. Article

    Open Access

    Diagnosing complications following cochlear implantation using transcutaneous ultrasound

    The aim of this study was to investigate the feasibility and reliability of transcutaneous ultrasound for the detection of complications after cochlear implantation.

    Robin Rupp, Vivian Thimsen, Matthias Balk in European Archives of Oto-Rhino-Laryngology (2022)

  8. Article

    Open Access

    Validity of tissue homogeneity in confocal laser endomicroscopy on the diagnosis of laryngeal and hypopharyngeal squamous cell carcinoma

    Confocal laser endomicroscopy (CLE) allows imaging of the laryngeal mucosa in a thousand-fold magnification. This study analyzes differences in tissue homogeneity between healthy mucosa and squamous cell carci...

    Matti Sievert, Marc Aubreville in European Archives of Oto-Rhino-Laryngology (2022)

  9. Article

    Open Access

    Impact of intraepithelial capillary loops and atypical vessels in confocal laser endomicroscopy for the diagnosis of laryngeal and hypopharyngeal squamous cell carcinoma

    Confocal laser endomicroscopy (CLE) allows surface imaging of the laryngeal and pharyngeal mucosa in vivo at a thousand-fold magnification. This study aims to compare irregular blood vessels and intraepithelia...

    Matti Sievert, Markus Eckstein in European Archives of Oto-Rhino-Laryngology (2022)

  10. Article

    Open Access

    Intraoperative free margins assessment of oropharyngeal squamous cell carcinoma with confocal laser endomicroscopy: a pilot study

    This pilot study aimed to assess the feasibility of intraoperative assessment of safe margins with confocal laser endomicroscopy (CLE) during oropharyngeal squamous cell carcinoma (OPSCC) surgery.

    Matti Sievert, Florian Stelzle in European Archives of Oto-Rhino-Laryngology (2021)

  11. Article

    Open Access

    Postoperative management of antithrombotic medication in microvascular head and neck reconstruction: a comparative analysis of unfractionated and low-molecular-weight heparin

    Free flap reconstruction is a valuable technique to preserve function in oncological head and neck surgery. Postoperative graft thrombosis is a dreaded risk. This study aims to compare low-dose unfractionated ...

    Matti Sievert, Miguel Goncalves in European Archives of Oto-Rhino-Laryngology (2021)