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  1. Article

    Open Access

    Advancing pathogen surveillance by nanopore sequencing and genotype characterization of Acheta domesticus densovirus in mass-reared house crickets

    Rapid and reliable detection of pathogens is crucial to complement the growing industry of mass-reared insects, in order to safeguard the insect colonies from outbreak of diseases, which may cause significant ...

    Fang Shiang Lim, Joel González-Cabrera, Jens Keilwagen in Scientific Reports (2024)

  2. Article

    Open Access

    Comparative genomics reveals low levels of inter- and intraspecies diversity in the causal agents of dwarf and common bunt of wheat and hint at conspecificity of Tilletia caries and T. laevis

    Tilletia caries and T. laevis, which are the causal agents of common bunt, as well as T. controversa, which causes dwarf bunt of wheat, threaten especially organic wheat farming. The three closely related fungal ...

    Somayyeh Sedaghatjoo, Bagdevi Mishra, Monika K. Forster, Yvonne Becker in IMA Fungus (2022)

  3. Article

    Open Access

    Genome wide association study of frost tolerance in wheat

    Winter wheat growing areas in the Northern hemisphere are regularly exposed to heavy frost. Due to the negative impact on yield, the identification of genetic factors controlling frost tolerance (FroT) and dev...

    Behnaz Soleimani, Heike Lehnert, Steve Babben, Jens Keilwagen in Scientific Reports (2022)

  4. Article

    Open Access

    Detecting major introgressions in wheat and their putative origins using coverage analysis

    Introgressions from crop wild relatives (CWRs) have been used to introduce beneficial traits into cultivated plants. Introgressions have traditionally been detected using cytological methods. Recently, single ...

    Jens Keilwagen, Heike Lehnert, Thomas Berner, Ekaterina Badaeva in Scientific Reports (2022)

  5. Article

    Open Access

    Chromosome-scale genome assembly provides insights into rye biology, evolution and agronomic potential

    Rye (Secale cereale L.) is an exceptionally climate-resilient cereal crop, used extensively to produce improved wheat varieties via introgressive hybridization and possessing the entire repertoire of genes necess...

    M. Timothy Rabanus-Wallace, Bernd Hackauf, Martin Mascher, Thomas Lux in Nature Genetics (2021)

  6. Article

    Open Access

    Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome

    Basenjis are considered an ancient dog breed of central African origins that still live and hunt with tribesmen in the African Congo. Nicknamed the barkless dog, Basenjis possess unique phylogeny, geographical...

    Richard J. Edwards, Matt A. Field, James M. Ferguson, Olga Dudchenko in BMC Genomics (2021)

  7. No Access

    Chapter

    The Gene and Repetitive Element Landscape of the Rye Genome

    In the genomics era, the rye genome has been given as little attention by researchers as no other entity in the most renowned triad of cereal crops in the tribe Triticeae: wheat, barley, and rye. Some of the r...

    Alexander V. Vershinin, Thomas Lux, Heidrun Gundlach in The Rye Genome (2021)

  8. Article

    Open Access

    Construction of a dense genetic map of the Malus fusca fire blight resistant accession MAL0045 using tunable genoty**-by-sequencing SNPs and microsatellites

    Although, the Pacific crabapple, Malus fusca, is a hardy and disease resistant species, studies relating to the genetics of its unique traits are very limited partly due to the lack of a genetic map of this inter...

    Ofere Francis Emeriewen, Klaus Richter, Thomas Berner, Jens Keilwagen in Scientific Reports (2020)

  9. No Access

    Article

    Genetic diversity and population structure in Beninese pigeon pea [Cajanus cajan (L.) Huth] landraces collection revealed by SSR and genome wide SNP markers

    Pigeon pea [Cajanus cajan (L.) Huth] is a valuable multipurpose crop locally used for household food security as well in traditional medicine in Benin. However, due to the neglected status of the crop, its geneti...

    Fiacre Zavinon, Hubert Adoukonou-Sagbadja in Genetic Resources and Crop Evolution (2020)

  10. Article

    Open Access

    Historical phenotypic data from seven decades of seed regeneration in a wheat ex situ collection

    Genebanks are valuable sources of genetic diversity, which can help to cope with future problems of global food security caused by a continuously growing population, stagnating yields and climate change. Howev...

    Norman Philipp, Stephan Weise, Markus Oppermann, Andreas Börner in Scientific Data (2019)

  11. No Access

    Article

    Aus Fehlern lernen — Wo binden Transkriptionsfaktoren an die DNA?

    Jan Grau, Stefan Posch, Jens Keilwagen in BIOspektrum (2019)

  12. Article

    Open Access

    Accurate prediction of cell type-specific transcription factor binding

    Prediction of cell type-specific, in vivo transcription factor binding sites is one of the central challenges in regulatory genomics. Here, we present our approach that earned a shared first rank in the “ENCOD...

    Jens Keilwagen, Stefan Posch, Jan Grau in Genome Biology (2019)

  13. No Access

    Protocol

    GeMoMa: Homology-Based Gene Prediction Utilizing Intron Position Conservation and RNA-seq Data

    GeMoMa is a homology-based gene prediction program that predicts gene models in target species based on gene models in evolutionary related reference species. GeMoMa utilizes amino acid sequence conservation, ...

    Jens Keilwagen, Frank Hartung, Jan Grau in Gene Prediction (2019)

  14. Article

    Open Access

    Towards map-based cloning of FB_Mfu10: identification of a receptor-like kinase candidate gene underlying the Malus fusca fire blight resistance locus on linkage group 10

    Breeding for resistance against the destructive fire blight disease of apples is the most sustainable strategy to control the menace of this disease, and has become increasingly important in European apple bre...

    Ofere Francis Emeriewen, Klaus Richter, Stefano Piazza in Molecular Breeding (2018)

  15. Article

    Open Access

    Combining RNA-seq data and homology-based gene prediction for plants, animals and fungi

    Genome annotation is of key importance in many research questions. The identification of protein-coding genes is often based on transcriptome sequencing data, ab-initio or homology-based prediction. Recently, it ...

    Jens Keilwagen, Frank Hartung, Michael Paulini, Sven O. Twardziok in BMC Bioinformatics (2018)

  16. Article

    Open Access

    Association genetics studies on frost tolerance in wheat (Triticum aestivum L.) reveal new highly conserved amino acid substitutions in CBF-A3, CBF-A15, VRN3 and PPD1 genes

    Understanding the genetic basis of frost tolerance (FT) in wheat (Triticum aestivum L.) is essential for preventing yield losses caused by frost due to cellular damage, dehydration and reduced metabolism. FT is a...

    Steve Babben, Edgar Schliephake, Philipp Janitza, Thomas Berner in BMC Genomics (2018)

  17. Article

    Open Access

    Genetic architecture and temporal patterns of biomass accumulation in spring barley revealed by image analysis

    Genetic map** of phenotypic traits generally focuses on a single time point, but biomass accumulates continuously during plant development. Resolution of the temporal dynamics that affect biomass recently be...

    Kerstin Neumann, Yusheng Zhao, Jianting Chu, Jens Keilwagen in BMC Plant Biology (2017)

  18. Article

    Open Access

    DiffLogo: a comparative visualization of sequence motifs

    For three decades, sequence logos are the de facto standard for the visualization of sequence motifs in biology and bioinformatics. Reasons for this success story are their simplicity and clarity. The number of i...

    Martin Nettling, Hendrik Treutler, Jan Grau, Jens Keilwagen in BMC Bioinformatics (2015)

  19. Article

    Open Access

    Separating the wheat from the chaff – a strategy to utilize plant genetic resources from ex situ genebanks

    The need for higher yielding and better-adapted crop plants for feeding the world's rapidly growing population has raised the question of how to systematically utilize large genebank collections with their wid...

    Jens Keilwagen, Benjamin Kilian, Hakan Özkan, Steve Babben in Scientific Reports (2014)

  20. Article

    Open Access

    Apples and oranges: avoiding different priors in Bayesian DNA sequence analysis

    One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or silencers, translation initiation sites, t...

    Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse in BMC Bioinformatics (2010)

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