4 Result(s)

Article

Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study

Results from preclinical studies suggest that age-dependent differences in host defense and the pulmonary renin–angiotensin system (RAS) are responsible for observed differences in epidemiology of acute respir...

Laura R. Schouten, Anton H. van Kaam, Franziska Kohse… in Annals of Intensive Care (2019)

Article

Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination

Lieuwe D. Bos, Cheryl Stips, Laura R. Schouten… in Intensive Care Medicine (2017)

Article

Transfusion of platelets, but not of red blood cells, is independently associated with nosocomial infections in the critically ill

Red blood cell (RBC) transfusion has been associated with nosocomial infection in the critically ill patients. However, this association may be confounded by length of stay, as prolonged intensive care unit (I...

Leo J. Engele, Marleen Straat, Ingeborg H. M. van Rooijen… in Annals of Intensive Care (2016)

Article

Effect of transfusion of fresh frozen plasma on parameters of endothelial condition and inflammatory status in non-bleeding critically ill patients: a prospective substudy of a randomized trial

Much controversy exists on the effect of a fresh frozen plasma (FFP) transfusion on systemic inflammation and endothelial damage. Adverse effects of FFP have been well described, including acute lung injury. H...

Marleen Straat, Marcella CA Müller, Joost CM Meijers, Mendi S Arbous… in Critical Care (2015)