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  1. Article

    Open Access

    The predictive validity for mortality of the driving pressure and the mechanical power of ventilation

    Outcome prediction in critically ill patients under invasive ventilation remains extremely challenging. The driving pressure (ΔP) and the mechanical power of ventilation (MP) are associated with patient-center...

    David M. P. van Meenen, Ary Serpa Neto in Intensive Care Medicine Experimental (2020)

  2. Article

    Open Access

    Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study

    Results from preclinical studies suggest that age-dependent differences in host defense and the pulmonary renin–angiotensin system (RAS) are responsible for observed differences in epidemiology of acute respir...

    Laura R. Schouten, Anton H. van Kaam, Franziska Kohse in Annals of Intensive Care (2019)

  3. Article

    Open Access

    Risk stratification using SpO2/FiO2 and PEEP at initial ARDS diagnosis and after 24 h in patients with moderate or severe ARDS

    We assessed the potential of risk stratification of ARDS patients using SpO2/FiO2 and positive end-expiratory pressure (PEEP) at ARDS onset and after 24 h.

    Luigi Pisani, Jan-Paul Roozeman, Fabienne D. Simonis in Annals of Intensive Care (2017)

  4. Article

    Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination

    Lieuwe D. Bos, Cheryl Stips, Laura R. Schouten in Intensive Care Medicine (2017)

  5. Article

    Open Access

    External validation of the APPS, a new and simple outcome prediction score in patients with the acute respiratory distress syndrome

    A recently developed prediction score based on age, arterial oxygen partial pressure to fractional inspired oxygen ratio (PaO2/FiO2) and plateau pressure (abbreviated as ‘APPS’) was shown to accurately predict mo...

    Lieuwe D. Bos, Laura R. Schouten, Olaf L. Cremer in Annals of Intensive Care (2016)