642 Result(s)
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Article
Li-**g Zhang
Science, Humanities and Social Sciences, multidisciplinary
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Riddle of the giant pandav
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Electron transfer by domain movement in cytochrome bc1
The cytochrome bc1 is one of the three major respiratory enzyme complexes residing in the inner mitochondrial membrane. Cytochrome bc1 transfers electrons from ubiquinol to cytochrome c and uses the energy thus r...
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Gene expression of gonadotropin-releasing hormone and its receptor in rat pancreatic cancer cell lines
The regression of experimental and clinical pancreatic cancers by treatment with gonadotropin-releasing hormone (GnRH) agonists or antagonists has been repeatedly reported and is usually presumed to result fro...
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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
During lymphocyte development, the assembly of genes coding for antigen receptors occurs by the combinatorial linking of gene segments. The stochastic nature of this process gives rise to lymphocytes that can ...
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Correction: Corrigenda: BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
Nature 415, 922–926 (2002). The number of CD4+ CD8+ thymocytes shown in Fig. 1a of this Letter should be × 107, and not × 106 as published. This error does not affect our conclusions.
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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
In diverse organisms, calorie restriction slows the pace of ageing and increases maximum lifespan. In the budding yeast Saccharomyces cerevisiae, calorie restriction extends lifespan by increasing the activity of...
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Over-expression of an Arabidopsis δ-OAT gene enhances salt and drought tolerance in transgenic rice
δ-OAT, ornithine-δ-aminotransferase, is the key enzyme involved in proline biosynthesis. In this study the Arabidopsis δ-OAT gene was transferred into rice (Oryza sativa L. ssp japonica cv. Zhongzuo 321), whose s...
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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4
Macrophages are pivotal constituents of the innate immune system, vital for recognition and elimination of microbial pathogens1. Macrophages use Toll-like receptors (TLRs) to detect pathogen-associated molecular ...
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Multimodal fast optical interrogation of neural circuitry
Our understanding of the cellular implementation of systems-level neural processes like action, thought and emotion has been limited by the availability of tools to interrogate specific classes of neural cells...
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Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
AMPK (AMP-activated protein kinase) senses cellular energy status to maintain a balance between ATP production and consumption and has important roles in regulating cell growth and proliferation. Here, crystal...
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Driving fast-spiking cells induces gamma rhythm and controls sensory responses
Cortical gamma oscillations (20-80 Hz) predict increases in focused attention, and failure in gamma regulation is a hallmark of neurological and psychiatric disease. Current theory predicts that gamma oscillat...
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Relationships between serum levels of thyroid hormones and serum concentrations of asymmetric dimethylarginine (ADMA) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP) in patients with Graves’ disease
Endothelial dysfunction as well as abnormal thyroid hormone levels may be responsible for increased cardiovascular risk in Graves’ disease (GD). Asymmetric dimethylarginine (ADMA) and N-terminal-pro-B-type natriu...
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Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
Regulatory T (Treg) cells are an important immunosuppressive lymphocyte population implicated in peripheral tolerance and in the pathogenesis of autoimmunity and cancer. The mechanisms accounting for Treg cell ac...
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Open AccessA Novel Solid-State Thermal Rectifier Based On Reduced Graphene Oxide
Recently, manipulating heat transport by phononic devices has received significant attention, in which phonon – a heat pulse through lattice, is used to carry energy. In addition to heat control, the thermal d...
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Open AccessHeteroepitaxial Growth of Single-Walled Carbon Nanotubes from Boron Nitride
The growth of single-walled carbon nanotubes (SWCNTs) with predefined structure is of great importance for both fundamental research and their practical applications. Traditionally, SWCNTs are grown from a met...
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Open AccessEvaluation of Ca3Co2O6 as cathode material for high-performance solid-oxide fuel cell
A cobalt-based thermoelectric compound Ca3Co2O6 (CCO) has been developed as new cathode material with superior performance for intermediate-temperature (IT) solid-oxide fuel cell (SOFC). Systematic evaluation has...
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The influence of the genetic and non-genetic factors on bone mineral density and osteoporotic fractures in Chinese women
To investigate the effects of genetic and non-genetic factors on bone mineral densities (BMDs) and osteoporotic fractures. This was a cross-sectional study to investigate the relationships between 18 SNPs and ...
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Open AccessTop–down fabrication of sub-nanometre semiconducting nanoribbons derived from molybdenum disulfide sheets
Developments in semiconductor technology are propelling the dimensions of devices down to 10 nm, but facing great challenges in manufacture at the sub-10 nm scale. Nanotechnology can fabricate nanoribbons from...
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Open AccessExtraordinary expansion of a Sorangium cellulosum genome from an alkaline milieu
Complex environmental conditions can significantly affect bacterial genome size by unknown mechanisms. The So0157-2 strain of Sorangium cellulosum is an alkaline-adaptive epothilone producer that grows across a w...
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Tailoring deposition and morphology of discharge products towards high-rate and long-life lithium-oxygen batteries
Lithium-oxygen batteries are an attractive technology for electrical energy storage because of their exceptionally high-energy density; however, battery applications still suffer from low rate capability, poor...
