18 Result(s)
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Open AccessGray matter covariations in autism: out-of-sample replication using the ENIGMA autism cohort
Autism spectrum disorder (henceforth autism) is a complex neurodevelopmental condition associated with differences in gray matter (GM) volume covariations, as reported in our previous study of the Longitudinal...
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Open AccessThe neuroanatomical substrates of autism and ADHD and their link to putative genomic underpinnings
Autism spectrum disorders (ASD) are neurodevelopmental conditions accompanied by differences in brain development. Neuroanatomical differences in autism are variable across individuals and likely underpin dist...
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Open AccessDiverging asymmetry of intrinsic functional organization in autism
Autism is a neurodevelopmental condition involving atypical sensory-perceptual functions together with language and socio-cognitive deficits. Previous work has reported subtle alterations in the asymmetry of b...
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Open AccessLinking functional and structural brain organisation with behaviour in autism: a multimodal EU-AIMS Longitudinal European Autism Project (LEAP) study
Neuroimaging analyses of brain structure and function in autism have typically been conducted in isolation, missing the sensitivity gains of linking data across modalities. Here we focus on the integration of ...
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Open AccessFine-grained topographic organization within somatosensory cortex during resting-state and emotional face-matching task and its association with ASD traits
Sensory atypicalities are particularly common in autism spectrum disorders (ASD). Nevertheless, our knowledge about the divergent functioning of the underlying somatosensory region and its association with ASD...
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Open AccessCorrection: Understanding the relationship between cerebellar structure and social abilities
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Article
Open AccessUnderstanding the relationship between cerebellar structure and social abilities
The cerebellum contains more than 50% of all neurons in the brain and is involved in a broad range of cognitive functions, including social communication and social cognition. Inconsistent atypicalities in the...
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Open AccessCross-sectional and longitudinal neuroanatomical profiles of distinct clinical (adaptive) outcomes in autism
Individuals with autism spectrum disorder (henceforth referred to as autism) display significant variation in clinical outcome. For instance, across age, some individuals’ adaptive skills naturally improve or ...
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Open AccessPatterns of connectome variability in autism across five functional activation tasks: findings from the LEAP project
Autism spectrum disorder (autism) is a complex neurodevelopmental condition with pronounced behavioral, cognitive, and neural heterogeneities across individuals. Here, our goal was to characterize heterogeneit...
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Open AccessSubtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium
Small average differences in the left-right asymmetry of cerebral cortical thickness have been reported in individuals with autism spectrum disorder (ASD) compared to typically develo** controls, affecting w...
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Open AccessModulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin
Autism spectrum disorder (ASD) has a high cost to affected individuals and society, but treatments for core symptoms are lacking. To expand intervention options, it is crucial to gain a better understanding of...
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Open AccessTowards robust and replicable sex differences in the intrinsic brain function of autism
Marked sex differences in autism prevalence accentuate the need to understand the role of biological sex-related factors in autism. Efforts to unravel sex differences in the brain organization of autism have, ...
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Open AccessFractionating autism based on neuroanatomical normative modeling
Autism is a complex neurodevelopmental condition with substantial phenotypic, biological, and etiologic heterogeneity. It remains a challenge to identify biomarkers to stratify autism into replicable cognitive...
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Open AccessGray matter covariations and core symptoms of autism: the EU-AIMS Longitudinal European Autism Project
Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influenc...
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Article
Greater cortical thickness in individuals with ASD
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Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder
Significant heterogeneity across aetiologies, neurobiology and clinical phenotypes have been observed in individuals with autism spectrum disorder (ASD). Neuroimaging-based neuroanatomical studies of ASD have ...
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Open AccessNetwork-specific sex differentiation of intrinsic brain function in males with autism
The male predominance in the prevalence of autism spectrum disorder (ASD) has motivated research on sex differentiation in ASD. Multiple sources of evidence have suggested a neurophenotypic convergence of ASD-...
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Open AccessAtypical lateralization of motor circuit functional connectivity in children with autism is associated with motor deficits
Atypical lateralization of language-related functions has been repeatedly found in individuals with autism spectrum conditions (ASC). Few studies have, however, investigated deviations from typically occurring...
