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  1. No Access

    Article

    Urine DNA biomarkers for hepatocellular carcinoma screening

    Hepatocellular carcinoma (HCC) occurs in a well-defined high-risk patient population, but better screening tests are needed to improve sensitivity and efficacy. Therefore, we investigated the use of urine circ...

    Amy K. Kim, James P. Hamilton, Selena Y. Lin, Ting-Tsung Chang… in British Journal of Cancer (2022)

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    Article

    Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2

    The poor prognosis and recurrence of HCC are majorly caused by intrahepatic metastasis. Delineating the molecular pathways mediating these processes may benefit develo** effective targeting therapies. Using ...

    Chi-Tan Hu, Jia-Ru Wu, Chuan-Chu Cheng, Sindy Wang… in Clinical & Experimental Metastasis (2011)

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    Article

    Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species

    Signal transduction exerted by the microenvironment around the primary tumor locus may trigger tumor metastasis especially at the migration stage. Sustained mitogen activated protein kinase (MAPK) signaling in...

    Wen-Sheng Wu, Jia-Ru Wu, Chi-Tan Hu in Cancer and Metastasis Reviews (2008)