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Article
Open AccessNovel urine cell-free DNA methylation markers for hepatocellular carcinoma
An optimized hepatocellular carcinoma (HCC)-targeted methylation next generation sequencing assay was developed to discover HCC-associated methylation markers directly from urine for HCC screening. Urine cell-...
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Article
Urine DNA biomarkers for hepatocellular carcinoma screening
Hepatocellular carcinoma (HCC) occurs in a well-defined high-risk patient population, but better screening tests are needed to improve sensitivity and efficacy. Therefore, we investigated the use of urine circ...
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Article
A narrative review of coronavirus disease 2019 (COVID-19): clinical, epidemiological characteristics, and systemic manifestations
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease which has had a rapid surge in cases and deaths since it is first documented in Wuhan, China, in December 2019. COVID-19 is caused by the B...
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Article
Open AccessSystemic deletion of Atp7b modifies the hepatocytes’ response to copper overload in the mouse models of Wilson disease
Wilson disease (WD) is caused by inactivation of the copper transporter Atp7b and copper overload in tissues. Mice with Atp7b deleted either globally (systemic inactivation) or only in hepatocyte recapitulate ...
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Article
Coffee consumption and liver-related hospitalizations and deaths in the ARIC study
Coffee consumption has been found to be associated with reduced risk of chronic conditions such as liver disease. However, less is known about the association between coffee and liver-related hospitalizations ...
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Article
Elevated ALT and GGT predict all-cause mortality and hepatocellular carcinoma in Taiwanese male: a case-cohort study
Evidence indicates a positive association between liver enzymes and the risk of death in Western countries; however, the evidence in Asian populations is scarce. We investigated the association between liver e...
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Article
Crystallinity and Mechanical Properties of Polypropylene-based Graphene Nanocomposites Studied with Atomic Force Microscopy and Raman Spectroscopy
Atomic force microscopy (AFM) and Raman spectroscopy were used to characterize the morphology and the local mechanical properties of polypropylene-based graphene nanocomposites. Amplitude Modulated AFM was use...
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Article
Mean Annual Temperature and Total Annual Precipitation Trends at Canadian Biosphere Reserves
This article examines instrumental climate records from a varietyof stations associated with the following Biosphere Reserves across Canada: (i) Waterton Lakes, (ii) Riding Mountain, (iii) Niagara Escarpment, ...
