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  1. No Access

    Article

    Cerebral metabolic changes in neurologically presymptomatic patients undergoing haemodialysis: in vivo proton MR spectroscopic findings

    To prospectively investigate and detect early cerebral metabolic changes in patients with end-stage renal disease (ESRD) by using in vivo proton MR spectroscopy (MRS).

    Ming-Lun Chiu, Chun-Wei Li, Jer-Ming Chang, I-Chan Chiang in European Radiology (2010)

  2. Article

    Open Access

    Clinical significance of serological biomarkers and neuropsychological performances in patients with temporal lobe epilepsy

    Temporal lobe epilepsy (TLE) is a common form of focal epilepsy. Serum biomarkers to predict cognitive performance in TLE patients without psychiatric comorbidities and the link with gray matter (GM) atrophy h...

    Chiung-Chih Chang, Chun-Chung Lui, Chen-Chang Lee, Shang-Der Chen in BMC Neurology (2012)

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    Article

    Diffusion-weighted imaging improves prediction in cognitive outcome and clinical phases in patients with carbon monoxide intoxication

    Changes in apparent diffusion coefficient (ADC) values often reflect tissue injury. Use of ADC as a surrogate marker to assess clinical phases has not been systemically applied in patients with carbon monoxide...

    Nai-Ching Chen, Chi-Wei Huang, Chun-Chung Lui, Chen-Chang Lee in Neuroradiology (2013)

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    Article

    Cancer Patient–Derived Circulating Microparticles Enhance Lung Metastasis in a Rat Model: Dual-Source CT, Cellular, and Molecular Studies

    This study aimed to test the hypothesis that lung cancer patient–derived circulating microparticles (LCC-MPs) enhance metastatic lung tumors in a rat model.

    Sheung-Fat Ko, Hon-Kan Yip, Yen-Yi Zhen, Chia-Chang Lee in Molecular Imaging and Biology (2016)

  5. Article

    Open Access

    Effects of Homocysteine on white matter diffusion parameters in Alzheimer’s disease

    The clinical features of Alzheimer’s disease (AD) are related to brain network degeneration, and hyperhomocysteinemia is related to greater white matter hyperintensities. We investigated the changes in four di...

    Chen-Chang Lee, Shih-Wei Hsu, Chi-Wei Huang, Wen-Neng Chang, Sz-Fan Chen in BMC Neurology (2017)

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    Article

    Apparent Diffusion Coefficient is a Useful Biomarker for Monitoring Adipose-Derived Mesenchymal Stem Cell Therapy of Renal Ischemic-Reperfusion Injury

    This study aimed to investigate the potential of apparent diffusion coefficient (ADC) for monitoring adipose-derived mesenchymal stem cell (ADMSC) therapy of renal ischemic-reperfusion injury (IRI).

    Sheung-Fat Ko, Hon-Kan Yip, Chen-Chang Lee, Chia-Chang Lee in Molecular Imaging and Biology (2018)

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    Article

    Renal Damages in Deoxycorticosterone Acetate–Salt Hypertensive Rats: Assessment with Diffusion Tensor Imaging and T2-map**

    This study aimed to investigate the feasibility of diffusion tensor imaging (DTI) and T2-map** to assess temporal renal damage in deoxycorticosterone acetate–salt (DOCA-salt) hypertensive rats and compare th...

    Sheung-Fat Ko, Hon-Kan Yip, Yen-Yi Zhen, Chi-Chih Hung in Molecular Imaging and Biology (2020)

  8. Article

    Open Access

    The use of individual-based FDG-PET volume of interest in predicting conversion from mild cognitive impairment to dementia

    Based on a longitudinal cohort design, the aim of this study was to investigate whether individual-based 18F fluorodeoxyglucose positron emission tomography (18F-FDG-PET) regional signals can predict dementia con...

    Shu-Hua Huang, Wen-Chiu Hsiao, Hsin-I Chang, Mi-Chia Ma in BMC Medical Imaging (2024)